Results 91 to 100 of about 1,647,229 (295)

Micro-structured tungsten, a high heat flux pulse proof material

Nuclear Materials and Energy, 2020
Micro structured tungsten is a new approach to address one of the main issues of tungsten as high heat flux (HHF) plasma facing material (PFM), which is its brittleness and its propensity to crack formation under pulsed, ELM like, heat loads (Loewenhoff ...
A. Terra, G. Sergienko, A. Kreter, Y. Martynova, M. Rasiński, M. Wirtz, Th. Loewenhoff, G. Pintsuk, D. Dorow-Gerspach, Y. Mao, D. Schwalenberg, L. Raumann, J.W. Coenen, S. Brezinsek, B. Unterberg, Ch. Linsmeier   +15 more
doaj   +1 more source

Origin of the high energy neutrino flux at IceCube

, 2017
We discuss the spectrum of the different components in the astrophysical neutrino flux reaching the Earth and the possible contribution of each component to the high-energy IceCube data. We show that the diffuse flux from cosmic ray interactions with gas
Carceller, J. M., Illana, J. I., Masip, M., Meloni, D.   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Advanced high temperature heat flux sensors [PDF]

To fully characterize advanced high temperature heat flux sensors, calibration and testing is required at full engine temperature. This required the development of unique high temperature heat flux test facilities. These facilities were developed, are in
Atkinson, W., Hobart, H. F., Strange, R. R.   +2 more
core   +1 more source

High photon flux table-top coherent extreme ultraviolet source

, 2014
High harmonic generation (HHG) enables extreme ultraviolet radiation with table-top setups. Its exceptional properties, such as coherence and (sub)-femtosecond pulse durations, have led to a diversity of applications.
Hoffmann, Armin, Hädrich, Steffen, Klenke, Arno, Krebs, Manuel, Limpert, Jens, Pervak, Vladimir, Pronin, Oleg, Rothhardt, Jan, Tünnermann, Andreas   +8 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Lattice Magnetic Walks

, 1993
Sums of walks for charged particles (e.g. Hofstadter electrons) on a square lattice in the presence of a magnetic field are evaluated. Returning loops are systematically added to directed paths to obtain the unrestricted propagators.
Blum, Thomas, Shapir, Yonathan
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Model-dependent high-energy neutrino flux from Gamma-Ray Bursts

, 2013
The IceCube Collaboration recently reported a stringent upper limit on the high energy neutrino flux from GRBs, which provides a meaningful constraint on the standard internal shock model.
Kumar, Pawan, Zhang, Bing
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source