Results 111 to 120 of about 1,647,229 (295)

Compact High Order Complete Flux Schemes

open access: yes, 2017
In this paper we outline the complete flux scheme for an advection-diffusion-reaction model problem. The scheme is based on the integral representation of the flux, which we derive from a local boundary value problem for the entire equation, including the source term. Consequently, the flux consists of a homogeneous part, corresponding to the advection-
ten Thije Boonkkamp, J.H.M.   +1 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Cryogenic flux-concentrator [PDF]

open access: yes, 1969
Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields.
Bailey, B. M., Brechna, H., Hill, D. A.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

High energy neutrinos: sources and fluxes

open access: yesJournal of Physics: Conference Series, 2006
We discuss briefly the potential sources of high energy astrophysical neutrinos and show estimates of the neutrino fluxes that they can produce. A special attention is paid to the connection between the highest energy cosmic rays and astrophysical neutrinos.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Color-magnetic flux tubes in quark matter cores of neutron stars

open access: yes, 2010
We argue that if color-superconducting quark matter exists in the core of a neutron star, it may contain a high density of flux tubes, carrying flux that is mostly color-magnetic, with a small admixture of ordinary magnetic flux.
Armen Sedrakian   +9 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Metallicity in the merger Seyfert galaxy NGC 6240

open access: yes, 2012
We have calculated the physical conditions throughout the NLR of the merger Seyfert galaxy NGC 6240 by modelling the observed optical and infrared line ratios.
Allen   +75 more
core   +1 more source

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