Results 121 to 130 of about 1,647,229 (295)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

High average-flux laser-driven neutron source

open access: yesNature Communications
Laser-driven neutron generation is an attractive alternative to more established methods for compact, short-pulse-duration neutron sources with applications in medical science, material science and imaging.
Simon Vallières   +12 more
doaj   +1 more source

High y+ Shear-Stress Turbulence Implementation for High Flux Isotope Reactor Narrow Channel Flows

open access: yesFluids
The research objective of this work was to improve the engineering predictions of the turbulence characteristics of flows in curved narrow channels. Such channel flows are commonly encountered in nuclear research and test reactors, with one of them being
Emilian Popov   +2 more
doaj   +1 more source

Super-Eddington fluxes during thermonuclear X-ray bursts

open access: yes, 2010
It has been known for nearly three decades that the energy spectra of thermonuclear X-ray bursts are often well-fit by Planck functions with temperatures so high that they imply a super-Eddington radiative flux at the emitting surface, even during ...
Cackett   +7 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Application value of high flux hemodialysis in uremic elders

open access: yesLinchuang shenzangbing zazhi, 2021
Objective To explore the application value of high flux hemodialysis(HFHD)in uremic elders.Methods From October 2018 to January 2020,a total of 102 uremic elders aged over 70 years were selected and randomized into two groups of study and control(n=51 ...
Chen Yan, Zhang Guang-lu
doaj  

Calorimeter probes for measuring high thermal flux [PDF]

open access: yes
Expendable, slug-type calorimeter probes were developed for measuring high heat-flux levels of 10-30 kW/sq cm in electric-arc jet facilities. The probes were constructed with thin tungsten caps mounted on Teflon bodies.
Russell, L. D.
core   +1 more source

Constraints on Galactic Neutrino Emission with Seven Years of IceCube Data [PDF]

open access: yes, 2017
The origins of high-energy astrophysical neutrinos remain a mystery despite extensive searches for their sources. We present constraints from seven years of IceCube Neutrino Observatory muon data on the neutrino flux coming from the Galactic plane.
Andeen, Karen
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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