Results 51 to 60 of about 19,526,654 (284)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

High resolution, high frame rate video technology development plan and the near-term system conceptual design [PDF]

open access: yes, 1990
The objective of the High Resolution, High Frame Rate Video Technology (HHVT) development effort is to provide technology advancements to remove constraints on the amount of high speed, detailed optical data recorded and transmitted for microgravity ...
Ziemke, Robert A.
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Lightweight High-Frame-Rate Block Coal Detection Method

open access: yesTaiyuan Ligong Daxue xuebao
【Purposes】Large pieces of coal can cause significant wear on the conveyor during transportation, affecting the safety of coal mining. To address the redundancy and inefficiency issues of traditional block coal detection methods, a more lightweight and ...
REN Qichao   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

High-Frame-Rate 3-D Vector Flow Imaging in the Frequency Domain

open access: yesApplied Sciences, 2020
Ultrasound vector Doppler techniques for three-dimensional (3-D) blood velocity measurements are currently limited by low temporal resolution and high computational cost.
Stefano Rossi   +3 more
doaj   +1 more source

Investigating the impact of high frame rates on video compression [PDF]

open access: yes2017 IEEE International Conference on Image Processing (ICIP), 2017
In this paper we investigate the impact of frame rate variation on HEVC video compression, and demonstrate that high frame rates (60+ fps) can lead to increased perceptual quality, notably in high bitrate environments. In order to quantify content dependence, a novel way of partitioning video sequences into categories is proposed.
Alex Mackin   +3 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Requirements and Hardware Limitations of High-Frame-Rate 3-D Ultrasound Imaging Systems

open access: yesApplied Sciences, 2022
The spread of high frame rate and 3-D imaging techniques has raised pressing requirements for ultrasound systems. In particular, the processing power and data transfer rate requirements may be so demanding to hinder the real-time (RT) implementation of ...
Claudio Giangrossi   +6 more
doaj   +1 more source

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