Results 81 to 90 of about 19,526,654 (284)
Sensors, 2019 We are studying a method based on the carrier frequency sweep for axial high resolution ultrasonic imaging to provide the range resolution that corresponds to the carrier wavelength.
Jing Zhu, Norio Tagawa
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Normalisation of shear test data for rate-independent compressible fabrics [PDF]
, 2007 This article describes a method of using both picture frame (PF) and bias extension (BE) tests together to characterize accurately the trellis shearing resistance of engineering fabrics under low in-plane tension conditions.
A. C. Long +8 more
core +1 more source
Research on distributed data acquisition software for high frame rate area detectors
He jishuBackgroundThe high frame rate area detector is the core detector for the major imaging-based experimental stations at the Shanghai HIgh repetitioN rate xfel and Extreme light facility (SHINE), and its data throughput is expected to reach more than 20 GB ...
SHANG Kunlin +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
High frame-rate and low frame-rate reconstructions of a dynamic contrast enhanced MRI dataset
, 2018 A supplementary video for Frank Ong's dissertation "Low Dimensional Methods for High Dimensional Magnetic Resonance Imaging". In the high frame-rate reconstruction, contrast injection dynamics faster than respiration are nicely shown, such as those in ...
Frank Ong (6075200)
core +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source