Results 191 to 200 of about 8,030,235 (300)

Clinical characteristics of children treated with high-frequency oscillation ventilation. [PDF]

Medicine (Baltimore)
Wen L, Guo X, Yang Y, Dang R, Zhang C, Chen F.   +5 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Characterization of the THz quantum cascade laser using fast superconducting hot electron bolometer

EPJ Web of Conferences, 2018
Lobanov Yu.V., Vakhtomin Yu.B., Pentin I.V., Khabibullin R.A., Shchavruk N.V., Smirnov K. V.   +5 more
doaj   +1 more source

The Value of the High-frequency Ultrasound System in Lacrimal Gland Prolapse Treatment. [PDF]

Plast Reconstr Surg Glob Open
Zhang G, Qiu Y, Gu T, Luo Y, Yan M, Wang Y, Chai H, Lu J.   +7 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The use of high-frequency ultrasound in diagnosing verrucous hemangioma. [PDF]

JAAD Case Rep
Di Carlo Del Vecchio L, Pacheco Millen de Mattos AL, Ferreira FR, de Paula Santos Miranda V, Castilho V.   +4 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Fast and the Very Fast: High-Frequency Oscillations in Alzheimer's Disease. [PDF]

Epilepsy Curr
Silva-Pérez M, Chin J.
europepmc   +1 more source

Developing High Frequency Foreign Exchange Trading Systems [PDF]

, 1980
Huser, Johannes, Schleucher, Heinrich
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