Results 71 to 80 of about 2,156,811 (323)
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Revisiting the trading activity of high-frequency trading firms around ultra-fast flash events
Financial InnovationWe investigate high-frequency traders’ behavior in the context of the fastest and most extreme price movements (EPMs) that can be observed in the market, specifically ultra-fast flash events, challenging the methodologies employed in the academic and ...
Christophe Desagre +2 more
doaj +1 more source
A New model for conducting high-frequency Trading Using Collaborative Cellular Learning Automata Algorithm and Extremal Optimization (CLA-EC-EO ) [PDF]
فصلنامه بورس اوراق بهادارIntroductionAt the same time as the speed of financial exchanges increases, many complications are also added to it, and the amount of attention paid to the role of human actors in it has faded, and the method of high-frequency trading is over time.
seyed ali paytakhti oskooe +2 more
doaj +1 more source
Influencing Factors Analysis of Crude Oil Futures Price Volatility Based on Mixed-Frequency Data
Applied Sciences, 2020 This article takes into account the form of mixed data as well as the peak and thick tail characteristics contained in the data characteristics, expands the GARCH-MIDAS (Generalized Autoregressive Conditional Heteroskedasticity-Mixed Data Sampling) model,
Congxin Wu +4 more
doaj +1 more source
High-Frequency Trading and Price Informativeness [PDF]
SSRN Electronic Journal, 2019 We study how stock price informativeness changes with the presence of high-frequency trading (HFT). Our estimate is based on the staggered start of HFT participation in a panel of international exchanges. With HFT presence market prices are a less reliable predictor of future cash flows and investment, even more so for longer horizons.
Gider, Jasmin +2 more
openaire +3 more sources
Transitions in the Stock Markets of the US, UK, and Germany [PDF]
, 2014 In an analysis of the US, the UK, and the German stock market we find a change in the behavior based on the stock's beta values. Before 2006 risky trades were concentrated on stocks in the IT and technology sector.
Raddant, Matthias, Wagner, Friedrich
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Risk and Return in High-Frequency Trading
Journal of Financial and Quantitative Analysis, 2018 We study performance and competition among firms engaging in high-frequency trading (HFT). We construct measures of latency and find that differences in relative latency account for large differences in HFT firms’ trading performance.
Matthew Baron +3 more
semanticscholar +1 more source
High-frequency trading with fractional Brownian motion
Finance and Stochastics, 2020 In the high-frequency limit, conditionally expected increments of fractional Brownian motion converge to a white noise, shedding their dependence on the path history and the forecasting horizon and making dynamic optimisation problems tractable.
P. Guasoni, Y. Mishura, M. Rásonyi
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source