Results 71 to 80 of about 152,057 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Solid State Transformer model for power flow calculations [PDF]

open access: yes, 2017
This paper presents the implementation of a Solid State Transformer (SST) model in OpenDSS. The goal is to develop a SST model that could be useful for assessing the impact that the replacement of the conventional iron-and-copper transformer with the SST
Guerra Sánchez, Luis Gerardo   +1 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Voltage inverter using high frequency transformer with PWM Modulation

open access: yesSemina: Ciências Exatas e Tecnológicas, 2004
This paper introduces a new frequency inverter topology with four forward converters, in a parallel topology configuration. These converters were modified to prevent one circuit to interfere on the functioning of other The resulting power is 800W, with ...
Ana Paula Bolognini   +2 more
doaj  

Transformers in High-Frequency Trading

open access: yesJournal of Physics: Conference Series
Abstract Transformer is a deep learning model that, having an innovative performance in many tasks, has uniquely and significantly modified all the cast of mind of the AI scientific community. In this paper, we introduce a Transformer model that is applied to 1-minute timescale in the EURUSD and GBPUSD instruments of forex trading.
Konstantinos T. Kantoutsis   +2 more
openaire   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Design optimization of high frequency transformer with controlled leakage inductance for current fed dual active bridge converter

open access: yesAIP Advances, 2018
Current fed dual active bridge converters for photovoltaic generation may typically require a given leakage or extra inductance in order to provide proper control of the currents. Therefore, the many researches have been focused on the leakage inductance
Tae-Uk Jung   +2 more
doaj   +1 more source

Transformation ray method: Controlling high frequency elastic waves (L) [PDF]

open access: yesThe Journal of the Acoustical Society of America, 2012
Elastic ray theory is a high frequency asymptotic approximation of solution of elastodynamic equation, and is widely used in seismology. In this paper, the form invariance under a general spatial mapping and high frequency wave control have been examined by transformation method.
Chang, Zheng   +3 more
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Design of electromagnetic components for EV battery chargers

open access: yesThe Journal of Engineering, 2019
This study focuses on the appropriate design of the inductive elements of the LLC converter based on a typical industrial approach, i.e. assuming to use standard parts available on the market from qualified manufacturers.
Andrea Stratta   +4 more
doaj   +1 more source

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