Results 61 to 70 of about 2,027,571 (338)

Lung Recruitment Strategies During High Frequency Oscillatory Ventilation in Preterm Lambs

Frontiers in Pediatrics, 2019
Background: High frequency oscillatory ventilation (HFOV) is considered a lung protective ventilation mode in preterm infants only if lung volume is optimized.
Martijn Miedema, Martijn Miedema, Karen E. McCall, Karen E. McCall, Elizabeth J. Perkins, Regina B. Oakley, Prue M. Pereira-Fantini, Anushi E. Rajapaksa, Anushi E. Rajapaksa, Anushi E. Rajapaksa, Andreas D. Waldmann, David G. Tingay, David G. Tingay, David G. Tingay, Anton H. van Kaam   +14 more
doaj   +1 more source

First Characterization of the Ultra-Shielded Chamber in the Low-noise Underground Laboratory (LSBB) of Rustrel Pays d'Apt [PDF]

, 1999
In compliance with international agreements on nuclear weapons limitation, the French ground-based nuclear arsenal has been decommissioned in its totality.
Arpesella, C. Dolabdjian, Collar, D. Bloyet, G. Waysand, Gorshov, Heusser, J.I. Collar, J.P. Bongiraud, Ph. Le Thiec   +9 more
core   +3 more sources

Noninvasive high-frequency oscillatory ventilation versus nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome: a randomized controlled trial

Journal of Maternal-Fetal & Neonatal Medicine, 2019
Background: Respiratory distress syndrome (RDS) is one of the main causes of mortality in premature neonates. Treatment of these neonates with invasive mechanical ventilation has side effects such as chronic pulmonary diseases.
Arash Malakian, Shiva Bashirnezhadkhabaz, M. Aramesh, M. Dehdashtian   +3 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

High-frequency percussive ventilation in acute respiratory failure

ERJ Open Research
Introduction High-frequency percussive ventilation (HFPV) is a ventilation mode characterised by high-frequency breaths. This study investigated the impact of HFPV on gas exchange and clinical outcomes in acute respiratory failure (ARF) patients during ...
Andrea Bruni, Giuseppe Neri, Gianmaria Cammarota, Vincenzo Bosco, Eugenio Biamonte, Letizia Troisi, Annalisa Boscolo, Paolo Navalesi, Federico Longhini, Eugenio Garofalo   +9 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

High-frequency oscillatory ventilation in children: a 10-year experience

Jornal de Pediatria (Versão em Português), 2013
Objectives: The aim of the study was to describe the experience with high-frequency oscillatory ventilation (HFOV) in a Portuguese Pediatric Critical Care Unit, and to evaluate whether HFOV allowed improvement in oxygenation and ventilation.
Marta Moniz, Catarina Silvestre, Pedro Nunes, Clara Abadesso, Ester Matias, Helena Loureiro, Helena Almeida   +6 more
doaj   +3 more sources

New insights in gill/buccal rhythm spiking activity and CO2 sensitivity in pre- and post-metamorphic tadpoles (Pelophylax ridibundus)

, 2013
Central CO2chemosensitivity is crucial for all air-breathing vertebrates and raises the question of itsrole in ventilatory rhythmogenesis. In this study, neurograms of ventilatory motor outputs recorded infacial nerve of premetamorphic and ...
Fiamma, Marie-Noëlle, Horcholle-Bossavit, Ginette, Quenet, Brigitte, Rivals, Isabelle, Similowski, Thomas, Straus, Christian   +5 more
core   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Expiratory high-frequency percussive ventilation: a novel concept for improving gas exchange

Respiratory Research, 2022
Background Although high-frequency percussive ventilation (HFPV) improves gas exchange, concerns remain about tissue overdistension caused by the oscillations and consequent lung damage.
Ferenc Peták, Gergely H. Fodor, Álmos Schranc, Roberta Südy, Ádám L. Balogh, Barna Babik, André Dos Santos Rocha, Sam Bayat, Davide Bizzotto, Raffaele L. Dellacà, Walid Habre   +10 more
doaj   +1 more source