Results 91 to 100 of about 1,471,692 (268)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

High gain reconfigurable symmetrical sector patch antenna loaded with parasitic elements

Zhongguo Jianchuan Yanjiu
Objectives To meet the demand for multifunctional antennas in shipborne communication systems, this paper proposes a novel high gain four-beam reconfigurable patch antenna based on the Yagi antenna.
Yuanxin HUANG, Li’an BIAN, Gaosheng LI, Yanxiu LI, Ranhao CHEN, Yan WANG   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Advancements in Mobile Communication: A Novel Sectoral Antenna Design Incorporating Magneto-Electric Curved Strip Dipoles and PRS Superstrate

IEEE Access
This research investigates the process of designing, practical implementation, and modification of features in a sectoral antenna for mobile communication technology.
N. Santalunai, S. Santalunai, W. Naktong, P. Chaipanya, P. Mesawad, P. Krachodnok   +5 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Lightweight, High-Efficiency, High-Dynamic-Response and Low-Ripple DC-DC Converters Based on Interleaved Magnetic Integrated Switched-Coupled Inductor for Electric Propulsion Aircraft

Aerospace
With the development of distributed electric propulsion aircraft, researching airborne high-efficiency, high-power-density, high-gain, high-dynamic and low-ripple, low-stress DC-DC that meets aviation standards is an urgent and profoundly challenging ...
Rui Guo, Hongkai Gao, Li Chen, Yiyi Zhang, Lei Wang   +4 more
doaj   +1 more source

A Novel Differential Fed High Gain Patch Antenna Using Resonant Slot Loading [PDF]

Radioengineering, 2018
Inspired by slotted waveguide antennas, a pair of resonant slots is placed in the center out of phase region of TM30 mode rectangular patch antenna which acts as a new radiating edge.
Z. Ahmed, M. M. Ahmed, M. B. Ihsan
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source