Results 231 to 240 of about 1,468,668 (317)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Performance measurement of high gain Landsman converter with ANFIS based MPPT and cascaded H-bridge thirty-one multilevel inverter in a single-phase grid-connected PV system. [PDF]

Sci Rep
Kumar NB, M UMR, Lakshminarayana P, Rao CNN, Veeranjaneyulu J.   +4 more
europepmc   +1 more source

High Gain Dual-frequency Dual-circularly Polarized Fabry Perot Resonant Cavity Antenna for Ku Band

Luo Wei, Xiaoxue Wang, Xin He, Yuqi Yang
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

High gain and wideband hybrid optical amplifier using bismuth-doped and neodymium-doped fibers for E-band applications. [PDF]

Sci Rep
Donodin A, Kiani L, Noor S, Forysiak W.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A Low-Profile Dual-Polarized High-Gain Low Cross-Polarization Phased Array for Ku-Band Satellite Communications. [PDF]

Sensors (Basel)
Huang Y, Zhang J, Li X, Qi Z, Lu F, Jiang H, Xue X, Zhu H, Guo X.   +8 more
europepmc   +1 more source

Low-power high-gain homogeneous feedback control for chain of integrators with disturbances

Salim Zekraoui, Daniele Astolfi, Jaime A. Moreno   +2 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Polarization-Insensitive Metasurface with High-Gain Large-Angle Beam Deflection. [PDF]

Materials (Basel)
Qiu H, Fang L, Xi R, Mu Y, Han J, Feng Q, Li Y, Li L, Zheng B.   +8 more
europepmc   +1 more source