ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Performance measurement of high gain Landsman converter with ANFIS based MPPT and cascaded H-bridge thirty-one multilevel inverter in a single-phase grid-connected PV system. [PDF]
Kumar NB +4 more
europepmc +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
A two-stage dc-dc converter with high voltage gain and reduced current ripple for efficient PV energy harvesting. [PDF]
Akca H.
europepmc +1 more source
High Efficiency Non-isolated DC-DC Converters with Wide Voltage Gain Range for Renewable Energies [PDF]
Yun Zhang, Shenghan Gao
openalex +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
A new quadratic step-up DC-DC converter with low voltage and current stresses. [PDF]
Hasanpour S, Nouri T.
europepmc +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Interleaved Quadratic Boost DC-DC Converter with Extended Voltage Gain and Reduced Switch Voltage Stress for Photovoltaic Applications. [PDF]
Ferreira D +7 more
europepmc +1 more source

