Results 121 to 130 of about 193,021 (301)

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Elevated hydrostatic pressure destabilizes VE-cadherin junctions in a time and shear stress dependent manner: An endothelium-on-chip study

APL Bioengineering
Despite the effects of shear stress on endothelial biology having been extensively researched, the effects of hydrostatic vascular pressure at extremely low shear stresses have been largely ignored. In the current study, we employ a microfluidic organ-on-
Pranav Vasanthi Bathrinarayanan, Thomas Abadie, Patricia Perez Esteban, D. Vigolo, M. J. H. Simmons, L. M. Grover   +5 more
doaj   +1 more source

Chemical Doping Engineering of Polarization and Topological Textures in van der Waals Ferroelectric CuInP2S6

Advanced Science, EarlyView.
Our work reports that Li⁺ doping in CuInP2S₆ induces coexistence of high‐ and low‐polarization states, which fosters a rich spectrum of topological polar textures, such as bubbles and labyrinth domains. An unconventional flexoelectric effect is also discovered, where strain gradients can mechanically manipulate these polarization states and their ...
Lei Gao, Wenhao Li, Fei Sun, Ziyi Zhou, Zhihao Shen, Jianwei Liang, He Jiang, Weiming Xiong, Weijin Chen, Xiaoyue Zhang, Yi Zhang, Xinzhi Liu, Yue Zheng   +12 more
wiley   +1 more source

High hydrostatic pressure stimulates microbial nitrate reduction in hadal trench sediments under oxic conditions

Nature Communications
Hadal trenches are extreme environments situated over 6000 m below sea surface, where enormous hydrostatic pressure affects the biochemical cycling of elements.
Na Yang, Yongxin Lv, Mukan Ji, Shiguo Wu, Yu Zhang   +4 more
doaj   +1 more source

The impact of high hydrostatic pressure maintenance after high-pressure torsion on phenomena during high hydrostatic pressure annealing

Materials Science and Engineering: A, 2022
Agnieszka Teresa Krawczynska, Michael Kerber, Przemyslaw Suchecki, Barbara Romelczyk-Baishya, Maciej Oskar Liedke, Maik Butterling, Eric Hirschmann, Andreas Wagner, Malgorzata Lewandowska, Daria Setman   +9 more
openaire   +3 more sources

Machine‐Learning‐Guided Design of Incommensurate Antiferroelectrics via Field‐Driven Phase Engineering

Advanced Science, EarlyView.
The key to enhancing the energy storage performance of antiferroelectrics lies in regulating the phase transition and reverse phase transition. A phase‐field‐machine learning framework is employed to predict the energy storage performance of Pb‐based incommensurate antiferroelectrics with multi‐scale regulation strategy, thereby revealing the dynamic ...
Ke Xu, Xiaoming Shi, Zhaochen Xi, Shouzhe Dong, Changqing Guo, Rongzhen Gao, Letao Yang, Jing Wang, Di Zhou, Houbing Huang   +9 more
wiley   +1 more source

Rapid Room‐Temperature Synthesis of Te4+‐Doped Cs2ZrCl6 Vacancy‐Ordered Double Perovskites With Tunable Luminescence Triggered by Extreme Conditions for Advanced Optical Thermometry and Manometry

Advanced Science, EarlyView.
Through utilizing a proposed rapid room‐temperature precipitation method, the Te4+‐doped Cs2ZrCl6 vacancy‐ordered doubles with intense STE emission were synthesized. Via using the extreme conditions, i.e., temperature and pressure, stimulus, the luminescence properties of the resulting compounds are significantly modulated, endowing their promising ...
Zhiyu Pei, Yeshan Wu, Shuailing Ma, Tian Cui, Laihui Luo, Peng Du   +5 more
wiley   +1 more source

All‐in‐One Underwater Quality Evaluation Metamaterial With Mechanical Robustness, Sound Attenuation, and Diffuse Reflection

Advanced Science, EarlyView.
In this work, a bioinspired all‐in‐one underwater quality evaluation metamaterial, combining sound attenuation, diffuse reflection, and mechanical robustness, is proposed based on jumping spider locomotion and human skeletal biomechanics. Meanwhile, a CNN‑driven quality evaluation framework is established for theoretically dimension‐reduced ...
Hongze Li, Zhenyu Li, Jinshui Yang, Jianhao Wu, Yidan Chen, Linzhi Wu, Hong Hu, Penglin Gao, Yegao Qu   +8 more
wiley   +1 more source

Pressure‐Induced Structural and Magnetic Evolution in Layered Antiferromagnet YbMn2Sb2

Advanced Electronic Materials, EarlyView.
Pressure tunes the delicate balance between structure, magnetism, and electronic states in quantum materials. In YbMn2Sb2, high‐pressure X‐ray and neutron diffraction reveal a trigonal‐to‐monoclinic transition near 3.5 GPa, accompanied by unconventional magnetic ordering.
Mingyu Xu, Matt Boswell, Aya Rutherford, Cheng Peng, Ying Zhou, Shuyang Wang, Zhaorong Yang, Antonio M. dos Santos, Haidong Zhou, Weiwei Xie   +9 more
wiley   +1 more source