Results 111 to 120 of about 17,685,281 (294)
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik +3 more
wiley +1 more source
The Boston Keratoprosthesis: Highs and Lows of Intraocular Pressure and Outcomes [PDF]
Keith H, Baratz, Kenneth M, Goins
openaire +2 more sources
Microrobots offer new opportunities for minimally invasive biomedical applications, including targeted therapy, in vivo sensing, and disease diagnosis. This review highlights biodegradable and retrievable strategies for post‐task management, focusing on material degradation, active retrieval, and the integration of both approaches to improve biosafety ...
Yiqi Yin, Miao Ma, Zhongyi Li, Jing Zhao
wiley +1 more source
Abstract Background Oral non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for analgesia in dogs with spontaneous chronic corneal epithelial defects (SCCEDs). Topical NSAIDs can delay epithelialisation and promote stromal melting, but the safety of systemic NSAIDs in SCCEDs is unknown.
Kaitlyn Scheunemann +2 more
wiley +1 more source
Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian +5 more
wiley +1 more source
Précis Treatment of acute angle-closure glaucoma with phacoemulsification combined with goniosynechialysis significantly improves patients’ visual acuity and reduce intraocular pressure; the preoperative condition has minimal influence on the treatment ...
Chan Xiong +8 more
doaj +1 more source
UNLABELLED STUDY OBJECTIVE. To determine the effect of different positional degrees on hemodynamics, especially central venous pressure and intraocular pressure, and a possible interrelationship, during laparoscopic surgery. SETTING.
Dekker PW +4 more
core +1 more source
In a cross‐sectional cohort of 104 participants, 7 T susceptibility separation MRI and diffusion imaging were combined with retinal imaging and visual evoked potentials to characterize visual pathway involvement in adrenomyeloneuropathy (AMN). Absolute diamagnetic susceptibility, a myelin‐associated measure, and fractional anisotropy (FA) showed ...
Ronghao Li +17 more
wiley +1 more source
Absolute and relative reductions in intraocular pressure.
Absolute and relative reductions in intraocular pressure.
Rui-Li Wei (305046) +4 more
core +1 more source
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy +2 more
wiley +1 more source

