Results 211 to 220 of about 17,685,281 (294)

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11632-11642, December 2026.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao   +7 more
wiley   +1 more source

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10931-10949, December 2026.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou   +5 more
wiley   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski   +6 more
wiley   +1 more source

Severe intraocular trauma in a fireman caused by a high‐pressure water jet

open access: yesClinical & Experimental Ophthalmology, 2011
Georgalas, I.   +4 more
openaire   +2 more sources

Optical‐Field Engineering and Instrumentation in Brillouin Microscopy

open access: yesAdvanced Photonics Research, Volume 7, Issue 11, November 2026.
Brillouin microscopy provides label‐free mechanical contrast through gigahertz light–acoustic interactions. This Review examines how optical‐field engineering and instrument architecture shape spectral precision, acquisition throughput, background rejection, spatial performance, and optical exposure.
Kangwen Tong   +5 more
wiley   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg   +19 more
wiley   +1 more source

Tubulointerstitial Nephritis With Uveitis Syndrome: A Case Report and Review of Literature

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT TINU syndrome should be considered in any child presenting with unexplained renal dysfunction and uveitis. Early recognition and a multidisciplinary approach involving nephrology and ophthalmology are essential to prevent irreversible renal and ocular damage.
Abdulelah Alshaiban
wiley   +1 more source

First‐in‐Human Regulatory T Cell‐Derived Exosomes Plus Ranibizumab for Refractory nAMD

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
ABSTRACT Persistent fluid despite intravitreal anti–vascular endothelial growth factor (VEGF) treatment remains common in neovascular age‐related macular degeneration (nAMD). Regulatory T cell–derived exosomes (TregExo) have preclinical immunomodulatory activity. To evaluate the safety and maximum tolerated dose (MTD) of intravitreal autologous TregExo
Ying Tian   +5 more
wiley   +1 more source

Clinical History and Burden of Gaucher Disease Type 3: A Cross‐Sectional Multinational Study

open access: yesJIMD Reports, Volume 67, Issue 6, November 2026.
ABSTRACT Gaucher disease Type 3 (GD3) is a rare genetic neurodegenerative disorder, characterized by heterogeneity in symptom burden, disease severity, and progression. There is limited evidence on the burden of GD3. This retrospective, cross‐sectional study estimated the burden of illness associated with GD3 using descriptive analyses of clinician ...
Eugen Mengel   +10 more
wiley   +1 more source

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