Results 131 to 140 of about 3,465,717 (304)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Two closely spaced microstrip patches with high isolation for full-duplex/MIMO applications. [PDF]
PLoS One, 2023 Tran HH, Nguyen TT, Nguyen Thi T.
europepmc +1 more source
The Unique Social Isolation Homosexual Adolescents Experience [PDF]
, 2006 A pioneering group of teenagers are identifying themselves as Gay, Lesbian, Bisexual, Transgender or Questioning (GLBTQ). GLBTQ adolescents experience a unique social isolation as compared with other minority and oppressed groups.
Finnerty, Marisa
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A Novel High-Isolation Dual-Polarized Patch Antenna with Two In-Band Transmission Zeros. [PDF]
Micromachines (Basel), 2023 Li F, Cheng YF, Wang G, Luo J.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Circularly polarized MIMO patch antenna with high isolation and wideband characteristics for WLAN applications. [PDF]
Heliyon, 2023 Kim-Thi P, The-Lam Nguyen T.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
High efficiency protoplast isolation from in vitro cultures and hairy roots of Maesa lanceolata [PDF]
, 2010 In vitro cultures of the medicinal plant Maesa lanceolata were established to enable the cultivation of plant material for the production of protoplasts.
Geelen, Danny, Lambert, Ellen
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source