Results 111 to 120 of about 3,480,511 (346)

High-level synthesis and secretion of laccase, a metalloenzyme biocatalyst, by the halophilic archaeon Haloferax volcanii. [PDF]

Methods Enzymol, 2021
Kasirajan L, Adams Z, Couto-Rodriguez RL, Gal D, Jia H, Mondragon P, Wassel PC, Yu D, Uthandi S, Maupin-Furlow JA.   +9 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Synthesis of Di-Tert-Butyldicyclohexyl-18-Crown-6 and Its Extraction of Strontium

He huaxue yu fangshe huaxue
90Sr(T1/2=28.9 a) is a highly toxic nuclide with high heat release and strong exothermic properties, and the content of 90Sr in radioactive waste must be accurately measured before disposal.
WANG Jing
doaj   +1 more source

Markedly different ATP requirements for rRNA synthesis and mtDNA light strand transcription versus mRNA synthesis in isolated human mitochondria [PDF]

, 1987
In isolated mitochondria from HeLa cells, the ATP requirements for mitochondral DNA (mtDNA) transcription and RNA processing can be satisfied by either endogenous synthesis, mainly through oxidative- phosphorylation, or by exogenous supply.
Attardi, Giuseppe, Gaines, George, Rossi, Cesare   +2 more
core  

Memory-Based High-Level Synthesis Optimizations Security Exploration on the Power Side-Channel [PDF]

, 2020
High-level synthesis (HLS) allows hardware designers to think algorithmically and not worry about low-level, cycle-by-cycle details. This provides the ability to quickly explore the architectural design space and tradeoffs between resource utilization ...
Blackstone, Jeremy, Hu, Wei, Kastner, Ryan, Mu, Dejun, Tai, Yu, Zhang, Lu   +5 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Prodigiosin: unveiling the crimson wonder – a comprehensive journey from diverse bioactivity to synthesis and yield enhancement

Frontiers in Microbiology
Prodigiosin (PG) is a red tripyrrole pigment from the prodiginine family that has attracted widespread attention due to its excellent biological activities, including anticancer, antibacterial and anti-algal activities. The synthesis and production of PG
Yonglin Lu, Derun Liu, Renhui Jiang, Ziyun Li, Xueyan Gao   +4 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Program Analysis and Source-Level Communication Optimizations for High-Level Synthesis [PDF]

, 2011
The use of hardware accelerators, e.g., with GPGPUs or customized circuits using FPGAs, are particularly interesting for accelerating data- and compute-intensive applications.
Alias, Christophe, Darte, Alain, Plesco, Alexandru   +2 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source