Results 111 to 120 of about 5,525,673 (387)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Spin-Based Neuron Model with Domain Wall Magnets as Synapse

, 2012
We present artificial neural network design using spin devices that achieves ultra low voltage operation, low power consumption, high speed, and high integration density.
Augustine, Charles, Panagopoulos, Georgios, Roy, Kaushik, Sharad, Mrigank   +3 more
core   +1 more source

Lithium plating accurate detection of lithium-ion capacitors upon high-rate charging

Green Energy and Intelligent Transportation
Lithium-ion capacitors (LICs) offer higher power density and longer cycle life compared to lithium-ion batteries, and greater energy density than supercapacitors, making them ideal for applications requiring both high energy and power density.
Shasha Zhao, Xianzhong Sun, Yabin An, Zhang Guo, Chen Li, Yanan Xu, Yi Li, Zhao Li, Xiong Zhang, Kai Wang, Yanwei Ma   +10 more
doaj   +1 more source

Simulations of Bio-Micro High Power Density Power Generation System for Zero Energy Building

CSID Journal of Infrastructure Development, 2019
The study of bio-micro high power density power generation system simulations for Zero Energy Building (ZEB) has been done, by analyzing the improvement momentum parameters for rotating impulse power turbines refers to the potential local bio-renewable ...
hariyotejo pujowidodo, Ahmad Indra Siswantara, Budiarso -   +2 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Energy Storage Control and Capacity Optimization for Regenerative Braking Power Fluctuation Mitigation Under Port Renewable Energy Integration

IET Renewable Power Generation
To solve the problems of power fluctuations, voltage violations, transformer overloading and restrictions on renewable energy consumption in ports, which are caused by fluctuation of renewables and regenerative braking power, an energy storage system ...
Jingyuan Yin, Junqiang He, Yiyuan Zhang, Zhezhi Chen, Xuelin He   +4 more
doaj   +1 more source

The density and thickness of quiescent prominences [PDF]

The electron density was determined for a number of quiescent prominences at various positions from the Stark effect. It was found that the intensity ratio of Mg I emission lines to SrII lines is independent of the observed electron density in the range ...
Hirayama, Tadashi
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

High power density of microhydraulic source by MEMS technology and its application

, 2021
Joon-wan KIM
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source