Results 51 to 60 of about 744,004 (263)

A Review of Research Methods for Stator Temperature Monitoring in PMSM

open access: yesCES Transactions on Electrical Machines and Systems
High-density permanent magnet synchronous motors (PMSMs) are widely used in electric drive systems. However, they are susceptible to temperature influences under complex operating conditions, and prolonged operation at high temperatures can first damage ...
Songze Zhao   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Linear quadratic regulator-based coordinated optimization for harmonic compensation in multifunctional grid-connected inverters

open access: yesInternational Journal of Electrical Power & Energy Systems
The increasing penetration of distributed energy resources (DERs) and electric vehicles (EVs) introduces widespread power electronic devices that significantly challenge harmonic mitigation in distribution systems.
Xianghua Peng   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Thrust Ripple Analysis and Precise Modeling of 12/13 Slot-Pole Linear Flux-Switching Permanent Magnet Motors

open access: yesCES Transactions on Electrical Machines and Systems
Linear flux-switching permanent magnet motors (LFSPMs) have been proposed for long stator applications such as rail transit. However, the conventional linear permanent magnet synchronous motor (LPMSM) suffers from thrust ripple, which degrades the motor ...
Qi Wang   +5 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Coordinated Capacitor Voltage Balancing Method for Cascaded H-Bridge Inverter with Supercapacitor and DC-DC Stage

open access: yesCES Transactions on Electrical Machines and Systems
Cascaded H-bridge inverter (CHBI) with supercapacitors (SCs) and dc-dc stage shows significant promise for medium to high voltage energy storage applications.
Ye Zhang   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Research progress in anode prelithiation techniques for lithium-ion energy storage devices

open access: yesCailiao gongcheng
Driven by the “dual-carbon” strategy,which accelerates energy structure transformation,the market demand for high-performance electrochemical energy storage systems has surged significantly.
WANG Hao   +5 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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