Results 81 to 90 of about 20,680,470 (306)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Research Advances in the Design and Control Technologies of Electric Spindle Motors for CNC Machine Tools

open access: yesEnergies
The electric spindle serves as a critical component in enabling a highly dynamic response, stable torque output, and precise motion control for the main cutting operations of CNC machine tools.
Jinhua Liang   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Enhanced Repetitive Control with Phase Compensation Based ADRC for Harmonic Suppression in Magnetically Suspended Rotor Under Strong Gyroscopic Effects

open access: yesCES Transactions on Electrical Machines and Systems
Magnetically suspended rotor (MSR) systems have gained widespread industrial adoption owing to their frictionless operation and exceptional reliability.
Yuxiang Zhu   +4 more
doaj   +1 more source

High power density molten carbonate fuel cells [PDF]

open access: yes, 1995
Our results to date indicate that the specific power of the MCFC can be increased from 1200 W/m{sup 2} to above 2000W/m{sup 2} through the use of advanced components such as the double doped LiFeO{sub 2} cathode and pressurized operation.
Myles, K. M.   +5 more
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Research on active damping voltage control considering leakage inductance of FOVRT transformer

open access: yesInternational Journal of Electrical Power & Energy Systems
The Flexible on-load voltage regulating transformer (FOVRT) is realized through the integration of a small power converter with the conventional on-load voltage regulator transformer.
Longfei Sun   +7 more
doaj   +1 more source

Configuration of the Power Reflux Hydro-Mechanical Transmission System

open access: yes
The hydro-mechanical transmission system (HMTS) operates either in power split transmission mode (PSTM) or power reflux transmission mode (PRTM). Although PRTM is often ignored as a transition mode, this study reveals that the HMTS operating in the PRTM ...
Jianhua Wang   +3 more
core   +1 more source

2014 CPES Annual Report [PDF]

open access: yes, 2014
Over the past two decades, CPES has secured research funding from major industries, such as GE, Rolls-Royce, Boeing, Alstom, ABB, Toyota, Nissan, Raytheon, and MKS, as well as from government agencies including the NSF, DOE, DARPA, ONR, U.S.
Center for Power Electronics Systems   +1 more
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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