Results 51 to 60 of about 22,287,702 (258)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Single‐Atom Metallophilic Sites for Liquid NaK Alloy Confinement toward Stable Alkali‐Metal Anodes

Advanced Science, 2023
Room temperature liquid NaK alloy is a promising candidate for high performance metal batteries, due to its dendrite‐free property and high energy density.
Junya Cui, Bowen Jin, Annan Xu, Jiale Li, Mingfei Shao   +4 more
doaj   +1 more source

Estudo do efeito anti-inflamatório do Etanercept utilizando-se o modelo de inflamação por carragenina, na bolsa de ar, em camundongos [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.A artrite reumatoide é uma doença inflamatória crônica de caráter autoimune que atinge cerca de 1% da
Mattei, Rodrigo Antônio
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Critical Bimetallic Phosphide Layer Enables Fast Electron Transfer and Extra Energy Supply for Flexible Quasi-Solid-State Zinc Batteries

Nano-Micro Letters
Highlights The critical bimetallic phosphide layer (CBPL) exhibits high electrical conductivity and forms heterostructures with NiCo-layered double hydroxide (NiCo-LDH), improving the electrical conductivity of the hybrid cathode (NiCo-P1.0).
Leixin Wu, Linfeng Lv, Yibo Xiong, Wenwu Wang, Xiaoqiao Liao, Xiyao Huang, Ruiqi Song, Zhe Zhu, Yixue Duan, Lei Wang, Zeyu Ma, Jiangwang Wang, Fazal ul Nisa, Kai Yang, Muhammad Tahir, Longbing Qu, Wenlong Cai, Liang He   +17 more
doaj   +1 more source

Development of a Power Factor Corrected High Current Supercapacitor Charger for a Surge Resistant UPS [PDF]

, 2012
The Uninterrupted Power Supplies (UPSs) provide short term power back up to electrical loads when the mains power fail. Usually UPSs employ battery packs as the energy storage device.
Zhang, Xu
core  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Operando interlayer expansion of multiscale curved graphene for volumetrically-efficient supercapacitors

Nature Communications
Supercapacitors deliver high power but are limited in compact applications by low volumetric energy and power densities. Two-dimensional materials like graphene, despite their high packing density, are hindered by poor ion transport kinetics.
Petar Jovanović, Meysam Sharifzadeh Mirshekarloo, Phillip Aitchison, Mahdokht Shaibani, Mainak Majumder   +4 more
doaj   +1 more source

High power diode lasers. Introduction

, 2022
S.1-3The motivation for writing this book is at least threefold: the extremely promising laser characteristics of high-power diode lasers; their vast application potential in production processes like welding, soldering, polymer joining, cutting, and ...
Poprawe, R.
core   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source