Results 121 to 130 of about 3,084,963 (320)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Discovery of the Hailin impact crater in northeast China

open access: yesMatter and Radiation at Extremes
A uniquely shaped impact structure, the Hailin impact crater, has been discovered in northeast China. The crater was formed on a granodiorite hillside and is an oval depression with asymmetric rim height and a maximum diameter of 1360 m.
Feng Yin   +3 more
doaj   +1 more source

The Impact of GaN Crystal Growth on Ammonia Flow Dynamics in Ammonothermal Processes

open access: yesCrystals
A computational fluid dynamics simulation was developed for the growth zone of gallium nitride crystallized using the alkaline ammonothermal method, considering the geometry of the seed crystals and the installation setup.
Marek Zak   +4 more
doaj   +1 more source

The pressure dependence of electron-phonon coupling in the organic superconductor $κ$-(BEDT-TTF)$_{2}$Cu(SCN)$_{2}$: A comparison of high pressure infrared reflectivity and Raman scattering experiments [PDF]

open access: yesarXiv, 2001
We determine the pressure dependence of the electron-phonon coupling constant in $\kappa$-(BEDT-TTF)$_{2}$Cu(SCN)$_{2}$ by comparison of high pressure Raman scattering and high pressure infrared reflectivity (IR) measurements. We use comparison of the IR reflection spectrum from deuterated and protonated samples to aid the deconvolution of several ...
arxiv  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

Superconductivity of thulium substituted clathrate hexahydrides at moderate pressure

open access: yesScientific Reports
Due to the BCS theory, hydrogen, the lightest element, would be the prospect of room-temperature superconductor after metallization, but because of the difficulty of the hydrogen metallization, the theory about hydrogen pre-compression was proposed that ...
Hongyu Huang   +6 more
doaj   +1 more source

Signature of superconductivity in pressurized La4Ni3O10-x single crystals grown at ambient pressure [PDF]

open access: yesarXiv
Nickelates have attracted enormous attention since the discovery of high-temperature superconductivity in La3Ni2O7 under high pressure. However, whether superconducting nickelate single crystals can be prepared at ambient pressure remains elusive.
arxiv  

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