Results 41 to 50 of about 3,084,963 (320)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

First-principles calculations of a high-pressure synthesized compound PtC [PDF]

open access: yes, 2005
First-principles density-functional method is used to study the recently high-pressure synthesized compound PtC. It is confirmed by our calculations that the platinum carbide has a zinc-blende ground-state phase at zero pressure and the rock-salt structure is a high-pressure phase.
arxiv   +1 more source

High-pressure crystallography [PDF]

open access: yesActa Crystallographica Section A Foundations of Crystallography, 2007
Since the late 1950's, high-pressure structural studies have become increasingly frequent, following the inception of opposed-anvil cells, development of efficient diffractometric equipment (brighter radiation sources both in laboratories and in synchrotron facilities, highly efficient area detectors) and procedures (for crystal mounting, centring ...
openaire   +3 more sources

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

From Molecules to Carbon Materials—High Pressure Induced Polymerization and Bonding Mechanisms of Unsaturated Compounds

open access: yesCrystals, 2019
With the development of high-pressure apparatus, in situ characterization methods and theoretical calculations, high-pressure technology becomes a more and more important method to synthesize new compounds with unusual structures and properties.
Xin Yang   +4 more
doaj   +1 more source

Time-dependent exchange creates the time-frustrated state of matter

open access: yesScientific Reports, 2022
Magnetic systems governed by exchange interactions between magnetic moments harbor frustration that leads to ground state degeneracy and results in the new topological state often referred to as a frustrated state of matter (FSM).
V. E. Valiulin   +3 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Longitudinal predictors of weapon involvement in middle adolescence: Evidence from the UK Millennium Cohort Study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023
Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley   +1 more source

New paradigm for configurational entropy in glass-forming systems

open access: yesScientific Reports, 2022
We show that on cooling towards glass transition configurational entropy exhibits more significant changes than predicted by classic relation. A universal formula according to Kauzmann temperature $${T}_{K}$$ T K is given: $$S={S}_{0}{t}^{n}$$ S = S 0 t ...
Aleksandra Drozd-Rzoska   +2 more
doaj   +1 more source

Observation of superconductivity in pressurized Weyl semimetal candidate TaIrTe4 [PDF]

open access: yesPhys. Rev. B 99, 020503 (2019), 2018
Here we report the observation of superconductivity in pressurized type-II Weyl semimetal (WSM) candidate TaIrTe4 by means of complementary high-pressure transport and synchrotron X-ray diffraction measurements. We find that TaIrTe4 shows superconductivity with transition temperature (TC) of 0.57 K at the pressure of ~23.8 GPa.
arxiv   +1 more source

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