Results 41 to 50 of about 2,402,463 (266)

From Molecules to Carbon Materials—High Pressure Induced Polymerization and Bonding Mechanisms of Unsaturated Compounds

Crystals, 2019
With the development of high-pressure apparatus, in situ characterization methods and theoretical calculations, high-pressure technology becomes a more and more important method to synthesize new compounds with unusual structures and properties.
Xin Yang, Xuan Wang, Yida Wang, Kuo Li, Haiyan Zheng   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Host-guest strategy for full-visible-spectrum piezochromism in halogen-bonded organic frameworks

Nature Communications
Full-visible-spectrum piezochromism is vital for advanced anti-counterfeiting and storage device applications, yet remains challenging. Polycyclic aromatic hydrocarbons represent a promising class of piezochromic materials.
Binhao Yang, Yixuan Wang, Jiaju Liang, Kaiyan Yuan, Ruidong Qiao, Tao Zhang, Xinyi Yang, Bo Zou   +7 more
doaj   +1 more source

In situ high-pressure spectroscopic studies using moissanite (4H-SiC) anvils

AIP Advances, 2018
We examined the Raman scattering and IR absorption spectroscopy of 4H-SiC and its performance as an anvil material for high-pressure UV-visible absorption spectroscopic measurements.
Jinbo Zhang, Xinli Zhao, Zhipeng Yan, Ye Yuan, Xin Li, Cuiying Pei, Haiyan Zheng, Lin Wang   +7 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Pressure stabilizes ferrous iron in bridgmanite under hydrous deep lower mantle conditions

Nature Communications
Earth’s lower mantle is a potential water reservoir. The physical and chemical properties of the region are in part controlled by the Fe3+/ΣFe ratio and total iron content in bridgmanite.
Li Zhang, Yongjin Chen, Ziqiang Yang, Lu Liu, Yanping Yang, Philip Dalladay-Simpson, Junyue Wang, Ho-kwang Mao   +7 more
doaj   +1 more source

Pressure-driven crystal symmetry and carrier concentration optimization for superior thermoelectric transport properties in layered AgCrSe2 [PDF]

Matter and Radiation at Extremes
Phase engineering has proven to be an effective strategy for achieving superior thermoelectric performance, while pressure is an excellent means of expanding the phase space of a material. In this paper, the effect of pressure-induced phase transition on
Zheng Bi, Dianzhen Wang, Yiyang Zhou, Yang Gao, Jing Zou, Fuyang Liu, Qiang Tao, Bin Yang, Huijuan Yue, Luhong Wang, Haozhe Liu, Yan Li, Pinwen Zhu   +12 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Redox reactions in subducted CaCO3–Fe–SiO2 as a potential source of superdeep diamond inclusions

Scientific Reports
CaCO3 is one of the most abundant carbonates at the Earth’s surface. It is transported into the mantle in substantial quantities via subducted slabs and participates in the deep mantle carbon cycle along with other mantle materials.
Mengqi Guo, Xinyang Li, Zhu Mao, Fangfei Li, Liang Li, Qiang Zhou   +5 more
doaj   +1 more source