Results 41 to 50 of about 18,903,450 (313)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Oscillatory mechanoluminescence of Mn2+-doped SrZnOS in dynamic response to rapid compression

Nature Communications
Photon emission may be continuously produced from mechanical work through self-recoverable mechanoluminescence (ML). Significant progress has been made in high-performance ML materials in the past decades, but the rate-dependent ML kinetics remains ...
Hao Wang, Tingting Zhao, Mei Li, Junlong Li, Ke Liu, Shang Peng, Xuqiang Liu, Bohao Zhao, Yanlong Chen, Jiao An, Xiaohui Chen, Sheng Jiang, Chuanlong Lin, Wenge Yang   +13 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Monolithic 45 Degree Deflecting Mirror as a Key Element for Realization of 2D Arrays of Laser Diodes Based on AlInGaN Semiconductors

Micromachines, 2023
In this study, we propose a solution for realization of surface emitting, 2D array of visible light laser diodes based on AlInGaN semiconductors. The presented system consists of a horizontal cavity lasing section adjoined with beam deflecting section in
Kiran Saba, Anna Kafar, Jacek Kacperski, Krzysztof Gibasiewicz, Dario Schiavon, Takao Oto, Szymon Grzanka, Piotr Perlin   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Development of a High‐Pressure Reactor Based on Liquid‐Flow Pressurisation to Facilitate Enzymatic Hydroxylation of Gaseous Alkanes [PDF]

, 2019
A new type of high‐pressure reactor based on liquid‐flow pressurisation using a HPLC pump has been developed. This high‐pressure reactor allows the easy and safe performance of reactions with gaseous alkanes under high‐pressures up to 10 MPa (100 atm ...
Chie Kasai, Shinya Ariyasu, Shoji, Osami, Stanfield, Joshua Kyle, Joshua Kyle Stanfield, Yoshihito Watanabe, Kasai, Chie, Kodama, Yusaku, Zhiqi Cong, Osami Shoji, Aiba, Yuichiro, Ariyasu, Shinya, Watanabe, Yoshihito, Yusaku Kodama, Yuichiro Aiba, Cong, Zhiqi   +15 more
core   +1 more source

NbN-based Josephson junctions grown by plasma-assisted molecular beam epitaxy

Communications Materials
Improved process for the growth of NbN by plasma-assisted molecular beam epitaxy (PAMBE) is needed for the fabrication of Josephson junctions, that are building blocks of qubits in quantum computers.
Artur Lachowski, Paweł Wolny, Krzysztof Dybko, Mikołaj Chlipała, Krzesimir Nowakowski-Szkudlarek, Mateusz Hajdel, Mikołaj Żak, Anna Feduniewicz, Marta Sawicka, Witold Chromiński, Ewa Grzanka, Czesław Skierbiszewski   +11 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

High pressure study of NaAlH4 by Raman spectroscopy up to 17 GPa

, 2006
A high-pressure Raman study was carried out on NaA1H(4) up to 17 GPa using the diamond anvil cell method. In the pressure region 2-5 GPa, several of the original modes split.
Sundqvist, Bertil,, Talyzin, Alexandr,
core   +1 more source

Electrical Transport of Pressure-Induced Magnetic Transition in YbMnBi2

Gaoya wuli xuebao
In this work, we performed systematic high-pressure electrical transport and Raman spectroscopy measurements on the topological semimetal YbMnBi2. The transport results reveal a pronounced evolution of the resistivity-temperature behavior with increasing
Tianqi WEN, Qi FENG, Meilun LI, Yi CHENG, Chuanlong LIN, Hong XIAO   +5 more
doaj   +1 more source