Results 141 to 150 of about 225,502 (309)

Tirame no ambiente: efeito de substâncias húmicas e iões Cu(II)

open access: yes, 2012
Doutoramento em QuímicaEm Portugal, o tirame é um dos fungicidas mais utilizados, cujas vendas aumentaram significativamente nos últimos anos, sendo também um dos fungicidas mais utilizados em todo o mundo.
Filipe, Olga Manuela Simão
core  

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Targeting the purine salvage pathway in in vitro models of cerebral ischemia [PDF]

open access: yes
An interruption of the blood supply to the brain, as occurs during ischemic stroke, results in a rapid decline of ATP levels and a subsequent loss of neuronal function and viability.
Zur Nedden, Stephanie
core  

Climate Change Threatens Micronutrient Density of European Winter Wheat

open access: yesAdvanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao   +17 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Dietary Risk Assessment of Cyromazine and Its Analogue Melamine in Evaporated and Infant Milk Samples in Nigeria [PDF]

open access: yesJournal of Food Quality and Hazards Control
Background: The safety of milk is considered as a significant public health consideration and has been a key concern for consumers worldwide. The concentrations of cyromazine and its metabolic product, melamine, and their dietary risk assessment are ...
A.O. Oyedeji, B.A. Odeyemi, L.A. Azeez
doaj  

Use of high pressure liquid chromatography in the study of liquid lubricant oxidation

open access: yes, 1982
The general principles of classical liquid chromatography and high-pressure liquid chromatography (HPLC) are reviewed, and their advantages and disadvantages are compared.
Morales, W.
core  

Determinação de cocaína em cédulas monetárias e mãos usando cromatografia líquida acoplada à espectrometria de massas e eletroforese capilar por detecção UV [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014.Esta tese de doutorado foi motivada pela preocupação com os riscos à saúde de pessoas que ...
Heller, Melina
core  

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