Results 41 to 50 of about 19,221,438 (289)
On achieving high accuracy and reliability in the calculation of relative protein–ligand binding affinities [PDF]
Proceedings of the National Academy of Sciences, 2012 We apply a free energy perturbation simulation method, free energy perturbation/replica exchange with solute tempering, to two modifications of protein–ligand complexes that lead to significant conformational changes, the first in the protein and the second in the ligand.
Lingle, Wang +2 more
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AxiomsThe approach to solving linear systems with structured matrices by means of the bidiagonal factorization of the inverse of the coefficient matrix is first considered in this review article, the starting point being the classical Björck–Pereyra algorithms
José-Javier Martínez
doaj +1 more source
Computing exponentials of essentially non-negative matrices entrywise to high relative accuracy [PDF]
Mathematics of Computation, 2013 A real square matrix is said to be essentially non-negative if all of its off-diagonal entries are non-negative. It has recently been shown that the exponential of an essentially non-negative matrix is determined entrywise to high relative accuracy by its entries up to a condition number intrinsic to the exponential function (Numer. Math.
Jungong Xue, Qiang Ye 0003
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L’éducation relative à l’environnement auprès des adultes : mouvances et repères [PDF]
, 2021 L’éducation relative à l’environnement (ERE) auprès des adultes est en plein essor. Les adultes, jeunes et moins jeunes, se retrouvent en effet dans un nombre grandissant de sphères d’activités qui proposent des éducations en matière d’environnement. Que
Villemagne, Carine, Sauvé, Lucie
core +1 more source
Accurate Computations with Block Checkerboard Pattern Matrices
MathematicsIn this work, block checkerboard sign pattern matrices are introduced and analyzed. They satisfy the generalized Perron–Frobenius theorem. We study the case related to total positive matrices in order to guarantee bidiagonal decompositions and some ...
Jorge Delgado +2 more
doaj +1 more source
An Improved Long-Period Precise Time-Relative Positioning Method Based on RTS Data
Sensors, 2020 The high precision positioning can be easily achieved by using real-time kinematic (RTK) and precise point positioning (PPP) or their augmented techniques, such as network RTK (NRTK) and PPP-RTK, even if they also have their own shortfalls.
Yangwei Lu +5 more
doaj +1 more source
Combined system of precise positioning of pilotless helicopter-type aircraft in the landing area [PDF]
ITM Web of Conferences, 2019 On-board equipment, ground equipment, and special software have been developed and tested that makes it possible to determine with high accuracy the relative coordinates of a helicopter-type unmanned aerial vehicle relative to a quick deployment runway ...
Antonov Andrey +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Accurate Computations with Generalized Pascal k-Eliminated Functional Matrices
MathematicsThis paper presents an accurate method to obtain the bidiagonal decomposition of some generalized Pascal matrices, including Pascal k-eliminated functional matrices and Pascal symmetric functional matrices.
Jorge Delgado +2 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source