Results 121 to 130 of about 2,671,831 (317)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Towards Automated DEM Generation from High Resolution Stereo Satellite Images

, 2008
High resolution stereo satellite imagery is well suited for the creation of digital surface models (DSM). In this paper, a system for highly automated DSM and orthoimage generation based on CARTOSAT-1 imagery is presented.
Krauss, Thomas, Reinartz, Peter, d'Angelo, Pablo, Hoja, Danielle, Lehner, Manfred   +4 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Combination of terrestrial Laser Scanning with high resolution panoramic Images for Investigations in Forest Applications and tree species recognition

, 2004
The management and planning of forests presumes the availability of up-to-date informaion on their current state. The relevant parameters like tree species, diameter of the bowl in defined heights an positions are usually represented by a forest ...
Reulke, Ralf, Haala, Norbert, Aschoff, Tobias, Thies, Michael   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Moving Target Signals in High Resolution Wide Swath SAR

, 2008
In this paper the impact of two high resolution wide swath synthetic aperture radar imaging techniques, extraction of signals from azimuth subsampled spectra and subpulse azimuth beamsteering on transmit, on ground moving target signals is analyzed ...
Krieger, Gerhard, Gabele, Martina
core  

Chebyshev gradient polynomials for high resolution surface and wavefront reconstruction

, 2018
A new data processing method based on orthonormal rectangular gradient polynomials is introduced in this work. This methodology is capable of effectively reconstructing surfaces or wavefronts with data obtained from deflectometry systems, especially ...
Oh, Chang Jin, Kim, Dae Wook, Burge, James H., Smith, Greg A., Aftab, Maham, Graves, Logan R.   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Corrigendum

Clinical Ophthalmology, 2011
Nelson DA, Burgansky-Eliash Z, Barash H, Loewenstein A, Barak A, Bartov E, Rock T, Grinvald AHigh-resolution widefield imaging of perfused capillaries without the use of contrast agentClinical Ophthalmology. 2011;5:1095-1106.The authors of this paper and
Nelson DA, Ruf A, Oaknin J, Burgansky-Eliash Z, Barash H, Izhaky D, Loewenstein A, Barak A, Bartov E, Rock T, Grinvald A   +10 more
doaj  

NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells

Frontiers in Molecular Biosciences
BackgroundMesenchymal stem cells, particularly those derived from dental pulp cells (DPSCs), hold promising potential for neuro-regenerative therapies due to their multipotency and accessibility.
Mattea Chirico, Maria Elena Pisanu, Emanuela Mari, Valeria Manganelli, Fanny Pulcini, Loreto Lancia, Rita Di Benedetto, Simona Delle Monache, Egidio Iorio, Vincenzo Mattei   +9 more
doaj   +1 more source