Results 241 to 250 of about 2,671,831 (317)
High-resolution imaging techniques to interrogate virus-host interactions. [PDF]
Amaya I, Spriggs CC.
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
A low-input Micro-C protocol for high-resolution 3D genome mapping. [PDF]
Shan F, Pei C, Xia S, Ling F.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A Targeted Spatial Transcriptomics Framework for a High-Resolution Human Skin Cell Atlas
Peake M +12 more
europepmc +1 more source
A high-resolution 3D genome map of kiwifruit provides insights into chromatin architecture and transcriptional activity. [PDF]
Xie S +8 more
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
An accelerated framework for high-resolution X-ray holographic reconstruction. [PDF]
Hu J +5 more
europepmc +1 more source

