Results 81 to 90 of about 5,140,621 (350)
, 2007 In the framework of the internal shock scenario, we model the broadband prompt emission of gamma-ray bursts (GRBs) with emphasis on the GeV-TeV bands, utilizing Monte Carlo simulations that include various processes associated with electrons and protons ...
Asano K. +6 more
core +4 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
4D modeling in high-rise construction
E3S Web of Conferences, 2018 High-rise construction is a complex construction process, requiring the use of more perfected and sophisticated tools for design, planning and construction management.
Balakina Anastasiya +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Regional approaches in high-rise construction
E3S Web of Conferences, 2018 The evolutionary process of high-rise construction is in the article focus. The aim of the study was to create a retrospective matrix reflecting the tasks of the study such as: structuring the most iconic high-rise objects within historic boundaries. The
Iconopisceva O.G., Proskurin G.A.
doaj +1 more source
Pulse generator using transistors and silicon controlled rectifiers produces high current pulses with fast rise and fall times [PDF]
, 1966 Electrical pulse generator uses power transistors and silicon controlled rectifiers for producing a high current pulse having fast rise and fall times.
Woolfson, M. G.
core +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
The carbon footprint of normal and high-strength concrete used in low-rise and high-rise buildings
Case Studies in Construction Materials, 2019 To reduce the mass of CO2 released into atmosphere by the construction industry, the performance strategy can be adopted. It is based on the use of High-Strength Concrete (HSC) in alternative to Normal-Strength Concrete (NSC).
A.P. Fantilli, O. Mancinelli, B. Chiaia
doaj +1 more source