Results 51 to 60 of about 22,833 (261)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Impact of window and air-conditioner operation behaviour on cooling load in high-rise residential buildings [PDF]
, 2022 Space cooling is an important building energy end-use that was found in recent years to be significantly impacted by occupant behaviours. However, the majority of previous studies ignored the interplay between the operation of windows and air ...
Pan, Wei, Du, Jia, Yu, Cong
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Three Creative Methods for High-Rise Building Design
Cubic JournalThis paper explores three innovative high-rise building design concepts to enrich urban environments by enhancing human perception, integrating cultural heritage and promoting sustainability.
Xi Deng +3 more
doaj +1 more source
Optimal Height Of Land Development – An Economic Perspective
Real Estate Management and Valuation, 2015 Sky-scrapers are rising in the panorama of big modern cities more and more often, becoming a symbol of dynamic growth and prestige. High-rise development appears to be an answer to the expanding demand for new residential and commercial space as urban ...
Żelazowski Konrad
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The Green Future Building Through Energy Optimization in High‐Rise Buildings
Energy Science & EngineeringThis study investigates the application of photovoltaic (PV) systems in 30‐meter high‐rise residential buildings in Tehran, evaluating the impact of four geographical orientations (north, south, east, and west).
Mobina Kalantari +3 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source