Results 81 to 90 of about 22,833 (261)

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Cost overruns analysis in high rise building and apartment projects

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020
Cost overruns is the lasting problem in construction industry, appears in all over the world. This research was conducted to assess the influence of each factor to the cost overruns in construction projects. The percentage of cost overruns caused by each
Nguyễn Lê Kế Nghiệp, Lưu Trường Văn, Nguyễn Hoài Nghĩa   +2 more
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The use of finite-element software to solve hygrothermal builiding physical problems related to insultating high rise buildings facades

, 2008
In The Netherlands high rise buildings from 1960 and before were hardly insulated. To improve the thermal performance of the buildings the facades may be insulated afterwards. The energy loss will be reduced and thermal comfort will be improved by higher
Schellen, H.L., Neuhaus, E., Hensen, Jan, Schijndel, van, A.W.M.   +3 more
core  

A Building Information Modeling-Based Life Cycle Assessment of the Embodied Carbon and Environmental Impacts of High-Rise Building Structures: A Case Study

High-rise buildings represent technological, urban, and life-style trends of the modern urban landscape, yet there are limited data regarding their embodied carbon and environmental impacts, particularly when compared to low- or mid-rise buildings. Given
Mahjoub Elnimeiri, Lijian Ma, Rahman Azari   +2 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The fire in high rise buildings

Informes de la Construccion, 1987
From the point of view of fire protection the high rise buildings have a special consideration, according to their design activities carried on, and fire protection system installed in them. In high rise buildings, difficulty of access by Extinction Services should be taken into account, as well as the impossibility of proceeding to make total ...
Núñez Astray, F., Campos Martínez, G., Labrador San Ronnualdo, J. A., Sanz Septién, M.   +3 more
openaire   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source