Results 121 to 130 of about 51,080,021 (356)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Tạp chí Khoa họcThis study investigates the potential of Artificial Intelligence (AI) to enhance the quality of physics education in Vietnamese high schools, aligning with the competency- based approach of the General Education Program 2018.
Nguyen Lam Duc* +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
TEACHING MATERIALS IN SOCIOLOGY LEARNING FROM VARIOUS VARIABLES IN HIGH SCHOOL
Sociological EducationThis study aims to determine the presentation of Sociology teaching materials during the Covid-19 pandemic seen from various variables (gender, class, age, school location, and school status) in high school.
Mila Noviana, Jepri Utomo
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Tarih Öğretiminde Menkıbelerin Kullanılması
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2011 Son yıllarda eğitim ve öğretim teknikleri alanında yapılan araştırmalarda büyük artışlar meydana gelmiştir. Tarih öğretimi alanında da bu gelişmelere paralel olarak bir takım yeni araştırmaların yapıldığıve anketlerin uygulandığıgörülmektedir.
Barış Sarıköse
doaj
Evaluation of the Use and Acceptance of an AR Mobile App in High School Students Using the TAM Model
InformationAugmented Reality (AR) has emerged as a promising educational tool, offering new opportunities to enhance learning through immersive and interactive experiences.
Antonio Amores-Valencia +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Jurnal Sosial HumanioraEducation has an important role in creating excellent human resources for the advancement of national development. However, in Indonesia, there are still gaps in equal access to education.
Bahalwan Apriyansyah +3 more
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