Results 111 to 120 of about 21,717,715 (348)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Rational design of a polyoxometalate intercalated layered double hydroxide: highly efficient catalytic epoxidation of allylic alcohols under mild and solvent-free conditions [PDF]

, 2016
Intercalation catalysts, owing to their modular and accessible gallery and unique interlamellar chemical environment, have shown wide application in various catalytic reactions.
Chen, Wei, Li, Tengfei, Miras, Haralampos N., Song, Yu-Fei, Wang, Zelin   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Photocatalytic CO2 reduction of Rhenium tricarbonyl complexes with high CO selectivity under visible light [PDF]

E3S Web of Conferences
Visible-light-driven photocatalytic CO2 reduction can address climate change and energy short-age. Homogenous photocatalysis converted CO2 to value chemicals have a straightforward procedure synthesis and CO2 conversion mechanism. Rhenium complexes based
Nguyen Ngoc Phuong, Phạm Duy Khanh, Nguyen Manh Tuan   +2 more
doaj   +1 more source

High‐power VHF tunable filters with high selectivity

Electronics Letters, 2014
A tunable helical bandpass filter with high selectivity designed for 30–88 MHz operation is presented. The two‐pole tunable filter is discretely tuned by connecting PIN switched capacitor banks at the terminal ends of the helix. The filter schematic provides two finite transmission zeros located in the lower and upper stopbands ...
Zhi‐Yuan Zhao, Jiang Chen, Lin Yang, Kun‐He Chen   +3 more
openaire   +1 more source

From the Bottom-Up: Toward Area-Selective Atomic Layer Deposition with High Selectivity†

Chemistry of Materials, 2018
Bottom-up nanofabrication by area-selective atomic layer deposition (ALD) is currently gaining momentum in semiconductor processing, because of the increasing need for eliminating the edge placement errors of top-down processing. Moreover, area-selective
A. Mackus, M. Merkx, W. Kessels
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cu‒S Covalent Bonds Enable the Anchoring of Single‐atom Cu on Layered MoS2 for Highly Selective and Active Photothermal Catalytic Conversion of CO2−H2O to Ethanol

Advanced Science
The catalytic conversion of CO2 into high‐value C2+ products offers a sustainable path toward carbon neutrality. However, traditional photocatalytic and thermal catalytic methods face challenges like low selectivity and yields.
Yingao Luo, Gaoli Chen, Zhongliao Wang, Sujuan Zhang, Xiuzhen Zheng, Sugang Meng, Shifu Chen   +6 more
doaj   +1 more source

Utilizing Imogolite Nanotubes as a Tunable Catalytic Material for the Selective Isomerization of Glucose to Fructose [PDF]

, 2018
The isomerization of glucose to fructose is an important step in the conversion of biomass to valuable fuels and chemicals. A key challenge for the isomerization reaction is achieving high selectivity towards fructose using recyclable and inexpensive ...
Olson, Nathaniel
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source