Results 131 to 140 of about 21,717,715 (348)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Sharp Response Microstrip LPF using Folded Stepped Impedance Open Stubs [PDF]
, 2013 A novel microstrip lowpass filter with high selectivity and wide stopband is proposed that comprises two lateral folded open stubs and a central mirrored semi-circle ended suppressing cell.
Ahmadi, A. +4 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
, 2019 This fact sheet is a step-by-step discussion of considerations that should be made when deciding where to build or move a high tunnel.
Maughan, Tiffany +2 more
openaire +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
CMS high-level trigger selection [PDF]
The European Physical Journal C, 2004 The CMS High-Level Trigger (HLT) is based on sets of dedicated commercial processors, whose goal is to reduce the Level-1 trigger rate of 100 kHz to ≈100 Hz, a value compatible with permanent storage of data. In this report the results from the recently published DAQ TDR are presented.
openaire +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
A Compact Dual-Band Quasi-Elliptic Filter Employing Meander-Line- and CRLH-Based SIW Triplets
Electromagnetic ScienceA compact dual-band quasi-elliptic filter with high selectivity is developed and investigated in this communication. It employs two hybrid-structure substrate integrated waveguide (SIW) triplets, which show completely inverse transfer responses under the
Yilong Zhu +4 more
doaj +1 more source
Student Performance may not Improve when Universities are Choosier [PDF]
We use unique administrative data from a leading Italian University to estimate whether the use of admission tests and conditional progression schemes are effective strategies to select high-performing students.
Carmen Aina +2 more
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source