Results 191 to 200 of about 21,717,715 (348)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

High-Selectivity Nonenzymatic Creatinine Sensor Using Electrografted Ionic Liquid and Nafion for Reliable Clinical Diagnostics. [PDF]

ACS Sens
Lin SH, Wang JC, Lin ZH, Kao FC, Wang HY.   +4 more
europepmc   +1 more source

Thymine DNA glycosylase is an RNA-binding protein with high selectivity for G-rich sequences. [PDF]

J Biol Chem, 2023
McGregor LA, Zhu B, Goetz AM, Sczepanski JT.   +3 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Toward high-selectivity CO₂ photoelectroreduction: mechanistic foundations, recent advances and challenges. [PDF]

Chem Sci
Zhou G, Wang Z, Gong J, Shen S, Zhong W.
europepmc   +1 more source

Structural Insights Into the High Selectivity of the Anti-Diabetic Drug Mitiglinide. [PDF]

Front Pharmacol, 2022
Wang M, Wu JX, Chen L.
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

A Phthalocyanine Optical Probe Responding to Cationic Surfactants Containing Long Carbon Chains with High Selectivity in Total Water Phase and Its Applications. [PDF]

Molecules
Zhang Y, Zhou T, Deng Y, Zheng X, Guo J, Huang P, Li D.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Multi-layer frequency selective surface wideband filter with high selectivity operating in L, S, and C bands. [PDF]

Sci Rep
Violi V, Brizi D, Monorchio A.
europepmc   +1 more source