Results 151 to 160 of about 24,544,639 (252)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Information Technology Newsletter July 2005

, 2005
University of Minnesota: Office of Information Technology. (2005). Information Technology Newsletter July 2005.
University of Minnesota: Office of Information Technology
core  

Antibacterial Furan Derivatives from the Flowers of Chrysanthemum indicum L.

BioResources
Furan derivatives are recognized for their diverse biological activities, particularly their antimicrobial properties. In this study, three new furan derivatives were isolated from acid-treated Chrysanthemum indicum flowers.
Van Phuong Nguyen, Thi Phuong Quynh Le, Nhu Da Le, Thi Hong Anh Nguyen, Hoang Giang Do, Thi Luyen Nguyen, Ngoc Minh Truong, Thi Thuy Duong, Tien Dat Nguyen   +8 more
doaj  

Recent Advances in Mulberry Processing and Drying Technologies: A Comprehensive Review. [PDF]

Foods
Quan X, Jiao Q, Lu Y, Liu M, Wang J, Li Y, Zhu S, Tian F, Song Z, Yan Y.   +9 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A Multifunctional Mesoporous Janus Separator With Optimized Mass Transport Regulation Enabling 800-Cycle Lithium-Oxygen Batteries. [PDF]

Adv Sci (Weinh)
Mu H, Liu A, Luo K, Pang Y, Xie C, Liu X, Luo Z, Zhu G, Wang Y, Liu Q, Tang Y.   +10 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Recent Advances in Polysaccharide-Based Encapsulation of Probiotics: Encapsulation Technologies, Material Properties, and Applications in Dairy Products. [PDF]

Foods
Ma J, Zhang M, Lan H, Chen W, Ma J.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Bioactive Substances in Sheep's Milk and Related Products as Components of Functional Foods. [PDF]

Molecules
Flis Z, Wieczorek J, Sady M, Molik E.
europepmc   +1 more source