Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
High performance of high-temperature-superconducting MPD thrusters: analytical MHD modeling and experimental demonstration. [PDF]
Zheng J +10 more
europepmc +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Physiological Responses of Grapevine Leaves to High Temperature at Different Senescence Periods. [PDF]
Guo S +7 more
europepmc +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
High-Temperature Deformation Behavior of Powder Metallurgy Ti-4Zr-6Al-0.6Si-0.5Mo Alloy. [PDF]
Li Z +6 more
europepmc +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
A Zwitterionic Copolymer at High Temperature and High Salinity for Oilfield Fracturing Fluids. [PDF]
Jing B +6 more
europepmc +1 more source
Lithium intercalated FeSe as a high-temperature superconducting ferromagnet. [PDF]
Hu Y +14 more
europepmc +1 more source
Investigation of high temperature rheological properties for attapulgite suspensions. [PDF]
Zheng W, Wang S, Bai L, Yang C.
europepmc +1 more source

