Results 51 to 60 of about 4,585,274 (405)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

High temperature oxidation behavior of γʹ-strengthened CoNi-base superalloys

open access: yesCorrosion Communications
Oxidation behavior of γʹ-strengthened CoNi-base superalloys was investigated with isothermal oxidation tests conducted in air at 800 and 900 °C, respectively, for 100 h.
Yingju Li   +5 more
doaj   +1 more source

High-temperature oxidation and erosion-resistant refractory coatings [PDF]

open access: yes, 1970
Various refractory coating systems were evaluated for rocket nozzle applications by actual rocket test firings. A reference is noted which identifies failure mechanisms and gives results of the firing tests for 18 coating systems.
Peterson, D. A., Winter, J. M.
core   +1 more source

UO2 surface oxidation by mixtures of water vapor and hydrogen as a function of temperature [PDF]

open access: yes, 2015
In the present work, X-Ray Photoelectron Spectroscopy (XPS) was used to study the effect of water vapor on the UO2 surface as a function of temperature. The experiments were performed in situ inside a high pressure chamber attached to the XPS instrument.
Casas Pons, Ignasi   +5 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Oxidation resistant, thoria-dispersed nickel-chromium-aluminum alloy [PDF]

open access: yes, 1973
Modified thoria-dispersed nickel-chromium alloy has been developed that exhibits greatly improved resistance to high-temperature oxidation. Additions of aluminum have been made to change nature of protective oxide scale entirely and to essentially ...
Baranow, S., Klingler, L. J.
core   +1 more source

High-Temperature Oxidation Behavior of Fe-1Cr-0.2Si Steel. [PDF]

open access: yesMaterials (Basel), 2020
In the case of Fe–1Cr–0.2Si steel, tube furnace oxidation was carried out for 120 min and 30 min. These studies, along with the high-temperature oxidation behavior of Fe–1Cr–0.2Si steel, were examined from 700 to 1100 °C.
Hao M, Sun B, Wang H.
europepmc   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Oxidation Induced Stresses in High-Temperature Oxidation of Steel: A Multiphase Field Study

open access: yesMetals, 2020
Oxide growth and the induced stresses in the high-temperature oxidation of steel were studied by a multiphase field model. The model incorporates both chemical and elastic energy to capture the coupled oxide kinetics and generated stresses.
Alireza Toghraee, Mohsen Asle Zaeem
doaj   +1 more source

High temperature oxidation of corrosion resistant alloys from machine learning

open access: yesnpj Materials Degradation, 2021
Parabolic rate constants, k p , were collected from published reports and calculated from corrosion product data (sample mass gain or corrosion product thickness) and tabulated for 75 alloys exposed to temperatures between ~800 and 2000 K (~500–1700 oC ...
Christopher D. Taylor, Brett M. Tossey
doaj   +1 more source

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