Results 41 to 50 of about 61,314 (294)
Image-based dynamic phenotyping reveals genetic determinants of filamentation-mediated beta-lactam tolerance [PDF]
, 2020 Antibiotic tolerance characterized by slow killing of bacteria in response to a drug can lead to treatment failure and promote the emergence of resistance.
Camacho, Rafael +8 more
core +2 more sources
High-throughput physical phenotyping of cell differentiation [PDF]
Microsystems & Nanoengineering, 2017 AbstractIn this report, we present multiparameter deformability cytometry (m-DC), in which we explore a large set of parameters describing the physical phenotypes of pluripotent cells and their derivatives. m-DC utilizes microfluidic inertial focusing and hydrodynamic stretching of single cells in conjunction with high-speed video recording to realize ...
Lin, Jonathan +7 more
openaire +4 more sources
COMPUTER APPROACHES TO WHEAT HIGH-THROUGHPUT PHENOTYPING [PDF]
Journal of Stress Physiology & Biochemistry, 2012 The growing need for rapid and accurate approaches for large-scale assessment of phenotypic characters in plants becomes more and more obvious in the studies looking into relationships between genotype and phenotype.
Afonnikov D. +6 more
doaj
High Throughput Neurological Phenotyping with MetaMap
European Scientific Journal, ESJ, 2022 The phenotyping of neurological patients involves the conversion of signs and symptoms into machine readable codes selected from an appropriate ontology. The phenotyping of neurological patients is manual and laborious. MetaMap is used for high throughput mapping of the medical literature to concepts in the Unified Medical Language System Metathesaurus
Daniel B. Hier +3 more
openaire +2 more sources
Computational Approaches to Phenotyping: High-Throughput Phenomics [PDF]
Proceedings of the American Thoracic Society, 2007 The recent completion of the Human Genome Project has made possible a high-throughput "systems approach" for accelerating the elucidation of molecular underpinnings of human diseases, and subsequent derivation of molecular-based strategies to more effectively prevent, diagnose, and treat these diseases.
Yves A, Lussier, Yang, Liu
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Leveraging Image Analysis for High-Throughput Plant Phenotyping
Frontiers in Plant Science, 2019 The complex interaction between a genotype and its environment controls the biophysical properties of a plant, manifested in observable traits, i.e., plant's phenome, which influences resources acquisition, performance, and yield.
Sruti Das Choudhury +4 more
doaj +1 more source
Plant Phenome Journal, 2021 High‐throughput phenotyping (HTP) has emerged as one of the most exciting and rapidly evolving spaces within plant science. The successful application of phenotyping technologies will facilitate increases in agricultural productivity.
Anna L. Casto +6 more
doaj +1 more source
Opportunities and limitations of crop phenotyping in southern european countries [PDF]
, 2019 ReviewThe Mediterranean climate is characterized by hot dry summers and frequent droughts. Mediterranean crops are frequently subjected to high evapotranspiration demands, soil water deficits, high temperatures, and photo-oxidative stress.
Baris Uzilday +11 more
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source