Results 31 to 40 of about 16,854 (198)

Presence of Chlamydia trachomatis and Mycoplasma spp., but not Neisseria gonorrhoeae and Treponema pallidum, in women undergoing an infertility evaluation: high prevalence of tetracycline resistance gene tet(M)

AMB Express, 2017
Chlamydia trachomatis, Mycoplasma spp., Neisseria gonorrhoeae and Treponema pallidum are sexually transmitted pathogens that threaten reproductive health worldwide.
Min Li, Xiaomei Zhang, Ke Huang, Haixiang Qiu, Jilei Zhang, Yuan Kang, Chengming Wang   +6 more
doaj   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Maternal Vaginal Colonization and Extended-Spectrum Beta-Lactamase-Producing Bacteria in Vietnamese Pregnant Women

Antibiotics, 2021
Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) resistance to commonly prescribed drugs is increasing in Vietnam. During pregnancy, ESBL-E may predispose women to reproductive tract infections and increases the risk for neonatal ...
Nguyen Thanh Viet, Vu Van Du, Nghiem Duc Thuan, Hoang Van Tong, Nguyen Linh Toan, Can Van Mao, Nguyen Van Tuan, Srinivas Reddy Pallerla, Dennis Nurjadi, Thirumalaisamy P. Velavan, Ho Anh Son   +10 more
doaj   +1 more source

Extended High‐Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High‐Risk Populations: A Cross‐Sectional Study

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Daisy Maharjan, Joshua Waters, Melissa Randolph, Benjamin Shuler, Julie Borum, Sheila Segura   +5 more
wiley   +1 more source

Lessons learned from comparing self-collected vs. physician-collected vaginal swabs for diagnosing infections in resource-limited settings: a 24-year review

DST
Introduction: Reproductive health is essential for women’s overall well-being, yet vaginal infections like Bacterial Vaginosis (BV), Candidiasis, and Trichomoniasis are prevalent and can lead to severe complications if left untreated.
Dr.Abhishek Lachyan, Dr.Niti Khunger, Dr.Rekha Bharti, Dr.Roshni Sharma, Dr.Krati Mehrotra, Dr.Abhay Goyal   +5 more
doaj   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

Developmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr., Mia V. Call, Noah M. LeFever, Mya Aviles‐Carlos, Nikki M. Dolphin, Paolo E. Forni   +5 more
wiley   +1 more source

Aerobic Bacterial Pathogens causing Vaginitis in Patients Attending A Tertiary Care Hospital and their Antibiotic Susceptibility Pattern

Journal of Pure and Applied Microbiology, 2019
Aerobic vaginitis (AV) is a condition in which the normal vaginal inhabitants are replaced by aerobic bacterial pathogens, triggering a vaginal immune response. AV should be treated promptly. The aim of the present study is to analyse the prevalence of
Lakshmi Krishnasamy, Chitralekha Saikumar, Govindasamy Kumaramanickavel   +2 more
doaj   +1 more source

Gram stains: a resource for retrospective analysis of bacterial pathogens in clinical studies. [PDF]

PLoS ONE, 2012
We demonstrate the feasibility of using qPCR on DNA extracted from vaginal Gram stain slides to estimate the presence and relative abundance of specific bacterial pathogens.
Usha Srinivasan, Sreelatha Ponnaluri, Lisa Villareal, Brenda Gillespie, Ai Wen, Arianna Miles, Brigette Bucholz, Carl F Marrs, Ram K Iyer, Dawn Misra, Betsy Foxman   +10 more
doaj   +1 more source