TAKAHASHI, Masao, TAKAHASHI, Tsuguhiro
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A direct A.C. to A.C. regenerative frequency and voltage converter
Includes bibliographical references.The reliable variable speed operation of an a. c. machine over a wide speed range is a problem that has received attention for some time.
Case, Michael James
core
The Tyrrhenian Link: A Next-Generation Electrical Infrastructure for the Mediterranean Grid
The evolution of transmission systems towards decarbonized and renewable energy-based generation has brought HVDC (High Voltage Direct Current) systems to the attention of stakeholders involved in infrastructure development, planning, and component ...
Marco Pasetti +5 more
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Assessing and managing potential health and safety issues related to high voltage direct current transmission lines [PDF]
The following report looks at assessing and managing potential health safety issues related to high voltage direct current transmission lines. The report includes information on HVDC transmission lines, HVDC electrical environment, biological effects of ...
Environmental Research Information, Inc.
core +1 more source
A Novel Ultra-High Voltage Direct Current Line Fault Diagnosis Method Based on Principal Component Analysis and Kernel Density Estimation. [PDF]
Zhang H, Gong Q.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Development and Validation of the High-Voltage Direct-Current Modular Multilevel Converter (HVDC-MMC) Model for Converter Transformer Protection Studies. [PDF]
Solak K, Rebizant W, Mieske F.
europepmc +1 more source

