Results 31 to 40 of about 135,885 (262)

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Single-Switch Soft-Switched High Voltage Gain Converter With Low Voltage Stress and Continuous Input Current

IEEE Open Journal of Power Electronics
This paper introduces a soft-switched high step-up converter applicable to photovoltaic systems. In the proposed topology, to further improve the voltage gain and reduce the components voltage stress, coupled inductors and voltage multiplier cell (VMC ...
Mohammad Reza Gholami, Siamak Khalili, Hosein Farzanehfard, Ehsan Adib, Hani Vahedi   +4 more
doaj   +1 more source

A Novel Non-Isolated High-Gain Non-Inverting Interleaved DC–DC Converter

Micromachines, 2023
High-gain DC–DC converters are being drastically utilized in renewable energy generation systems, such as photovoltaic (PV) and fuel cells (FC). Renewable energy sources (RES) persist with low-level output voltage; therefore, high-gain DC–DC converters ...
Farhan Mumtaz, Nor Zaihar Yahaya, Sheikh Tanzim Meraj, Narinderjit Singh Sawaran Singh, Ghulam E Mustafa Abro   +4 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Modified Two-Channel LLC Resonant Converter With Optimal Efficiency for Wide Input Voltage Applications

IEEE Access, 2023
A modified two-channel LLC resonant converter with optimal efficiency for wide input voltage applications. The converter has the same voltage gain and power handing ability as conventional full-bridge (FB) resonant converter, but the hardware cost is ...
Linlin Pi
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Transformerless high voltage gain Y-source converter with reduced switch stress

e-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper introduces a novel Y-source converter, which utilises a three winding coupled inductor and a switched inductor boost module. In contrast to the conventional layout, the Y source converter has a repositioning of the switch from the load side to
S.M. NithyaDevi, Vijayakumar Krishnasamy, J. Divya Navamani   +2 more
doaj   +1 more source

Ultra high gain step up DC/DC converter based on switched inductor and improved voltage lift technique for high‐voltage applications

IET Power Electronics, 2022
Voltage lift is a well‐known technique to improve the voltage gain of the converter. A combination of switched inductor and the conventional voltage lift technique can be used to achieve high gain, but the semiconductor's stress is still high.
Shahrukh Khan, Mohammad Zaid, Marif Daula Siddique, Atif Iqbal   +3 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source