Results 111 to 120 of about 1,616,802 (377)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Hyperholomorphic functions and higher order partial differential equations in the plane [PDF]
, 1990 R. Z. Yeh
openalex +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Comparing Sectoral Investment and Employment Specialisation of EU Regions: A Spatial Econometric Analysis [PDF]
EMU is accompanied by increased market integration and factor mobility ? especially of the production factor capital. Up to date, there is no clear indication concerning the specialisation tendencies to be expected due to these impacts.
Claudia Stirboeck
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Access to Higher Education. A Review of the Literature with a Focus on Central and Eastern Europe
Sociologie Românească, 2013 The article is reviewing the mainstream literature on the issue of expansion of higher education and the evolution of inequalities of access in tertiary cycle, with a special concern for the case of Central and Eastern Europe, and for two cases which are
Adrian Hatos
doaj
Reducing Energy Costs for Gas Preheating through Gas-Dynamic Stratification in the Leontiev Tube [PDF]
Problems of the Regional EnergeticsThe main objectives of this study are to reduce the energy consumption for gas preheating and improve the efficiency of compression systems using gas-dynamic temperature stratification in the Leontiev tube.
Kovalnogov V.N. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A survey on hyperbolicity of projective hypersurfaces
, 2011 These are lecture notes of a course held at IMPA, Rio de Janiero, in september 2010: the purpose was to present recent results on Kobayashi hyperbolicity in complex geometry.
Diverio, Simone, Rousseau, Erwan
core