Results 51 to 60 of about 15,174 (140)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Oscillations in Higher-Order Neutral Differential Equations

open access: yesCanadian Journal of Mathematics, 1993
AbstractConsider the n-th order (n ≥ 1 ) neutral differential equation where σ1 < σ 2 < ∞ and μ and η are increasing real-valued functions on [Ƭ1, Ƭ2] and [σ1, σ2] respectively. The function μ is assumed to be not constant on [Ƭ1, Ƭ2] and [Ƭ1, Ƭ2] for every Ƭ ∈ (Ƭ1, Ƭ2) similarly, for each σ ∈ (σ1, σ2), it is supposed that r\ is not constant on
Philos, C. G.   +2 more
openaire   +4 more sources

Truncated and higher order differentials [PDF]

open access: yes, 1995
In [6] higher order derivatives of discrete functions were considered and the concept of higher order differentials was introduced. We introduce the concept of truncated differentials and present attacks on ciphers presumably secure against differential attacks, but vulnerable to attacks using higher order and truncated differentials.
openaire   +2 more sources

Higher-Order Distributions for Differential Linear Logic [PDF]

open access: yes, 2019
Abstract Linear Logic was introduced as the computational counterpart of the algebraic notion of linearity. Differential Linear Logic refines Linear Logic with a proof-theoretical interpretation of the geometrical process of differentiation. In this article, we construct a polarized model of Differential Linear Logic satisfying computational ...
Kerjean, Marie, Lemay, Jean-Simon
openaire   +3 more sources

Higher order numerical differentiation on the Infinity Computer [PDF]

open access: yesOptimization Letters, 2010
There exist many applications where it is necessary to approximate numerically derivatives of a function which is given by a computer procedure. In particular, all the fields of optimization have a special interest in such a kind of information. In this paper, a new way to do this is presented for a new kind of a computer -- the Infinity Computer ...
openaire   +4 more sources

Oscillations of Higher Order Neutral Differential Equations

open access: yesRocky Mountain Journal of Mathematics, 1995
Consider linear neutral differential equations of odd order in the form \[ [x(t)- P(t) x(t-\tau)]^{(n)}+ Q(t) x(t-\sigma(t))= 0,\tag{1} \] where \(n\geq 1\), \(\tau> 0\), \(P\), \(Q\), \(\sigma\in C([t_0, \infty),\mathbb{R}^+)\) and \(\lim_{t\to \infty} (t- \sigma(t))= \infty\).
Zhang, B.G., Yu, J.S., Wang, Z.C.
openaire   +4 more sources

Nonoscillation of higher order functional differential equations

open access: yesJournal of Mathematical Analysis and Applications, 1983
The objective of this paper is to obtain sufficient conditions for all solutions of the forced higher order nonlinear functional differential equation \((a(t)x')^{(n-1)}+f(x(g(t)))=r(t)\) to be nonoscillatory. For this purpose, the asymptotic behavior of oscillatory solutions is discussed. The main results refer to nonlinearities of the type \(| f(x)| \
openaire   +2 more sources

The theory of higher order M-adic differentials

open access: yesJournal of Algebra, 1974
AbstractIn [1], Mount and Villamayor define the module of n-order differentials of a coefficient ring R over a subring K. This module is denoted Dn(RK) and is useful in classifying singularities of morphisms of algebraic varieties. D1(RK) is the universal object for K-derivations of R. Mount and Villamayor define a generalization of K-derivation called
openaire   +2 more sources

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