Results 81 to 90 of about 347,643 (299)

Network Traffic Data Augmentation Using WGAN Model Guided by LLM

Sensors
The Internet of Things (IoT) continues to expand across critical infrastructures, enabling automation, efficiency, and data driven decision making; yet, reliable device identification from network traffic remains hampered by severe class imbalance that ...
Jumanah Hmoud Alyoubi, Miada Almasre, Aishah Aseeri, Alanoud Subahi, Norah Al-Malki   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Role of Point-of-care Glucose Monitoring Devices in Initiating Treatment for Neonatal Hypoglycaemia: A Cross-sectional Study [PDF]

Indian Journal of Neonatal Medicine and Research
Introduction: Detection and prompt management of hypoglycaemia among at-risk and symptomatic neonates is crucial to prevent neurodevelopmental morbidity. Laboratory-based Formal Random Blood Sugar (FRBS) is the gold standard for estimating Blood Glucose (
Amina Shamsudeen, Roseline K Madathil, Kunjumol P Mathew, Krishna K Diwakar   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The expression profile and clinic significance of the SIX family in non-small cell lung cancer

Journal of Hematology & Oncology, 2016
Background The SIX family homeobox genes have been demonstrated to be involved in the tumor initiation and progression, but their clinicopathological features and prognostic values in non-small cell lung cancer (NSCLC) have not been well defined.
Qian Liu, Anping Li, Yijun Tian, Yu Liu, Tengfei Li, Cuntai Zhang, Jennifer D. Wu, Xinwei Han, Kongming Wu   +8 more
doaj   +1 more source

Accelerating the performance of district health systems towards achieving UHC via twinning partnerships

BMC Health Services Research, 2020
Background A twinning partnership is a formal and substantive collaboration between two districts to improve their performance in providing primary healthcare services.
Mesele Damte Argaw, Binyam Fekadu Desta, Mengistu Asnake Kibret, Melkamu Getu Abebe, Wubishet Kebede Heyi, Elias Mamo, Tesfaye Gebru, Chala Gelan, Bekele Belayhun Tefera, Temesgen Ayehu Bele   +9 more
doaj   +1 more source

Fundamental groupoids of k-graphs [PDF]

, 2003
k-graphs are higher-rank analogues of directed graphs which were first developed to provide combinatorial models for operator algebras of Cuntz-Krieger type.
Pask, David, Quigg, John, Raeburn, Iain
core   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A Novel Hyper-Heuristic Algorithm with Soft and Hard Constraints for Causal Discovery Using a Linear Structural Equation Model

Entropy
Artificial intelligence plays an indispensable role in improving productivity and promoting social development, and causal discovery is one of the extremely important research directions in this field. Acyclic directed graphs (DAGs) are the most commonly
Yinglong Dang, Xiaoguang Gao, Zidong Wang   +2 more
doaj   +1 more source