Results 171 to 180 of about 15,964,509 (348)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Guidelines for Authors

open access: yesTuning Journal for Higher Education, 2016
Editorial Team Tuning Journal for Higher Education
doaj   +2 more sources

TJHE Ethical Guidelines for Publication

open access: yesTuning Journal for Higher Education, 2016
Editorial Team Tuning Journal for Higher Education
doaj   +2 more sources

'Wish you were here': Managers' experiences of hybrid work in higher education. [PDF]

open access: yesPLoS One
Tinnerholm Ljungberg H   +7 more
europepmc   +1 more source

Internationalization of Higher Education Institutions: The Case of Four HEIs in the Philippines

open access: diamond, 2017
Ma. Florecilla C. Cinches   +3 more
openalex   +2 more sources

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