Results 31 to 40 of about 7,501,853 (298)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Alexithymia and aggressiveness in old age: Mediation by impulsivity and emotion dysregulation
Psychology, Society & Education, 2022 Aggressiveness is prevalent in old age, and to adapt treatments and diminish the accompanying damage to the self and others, it is important to understand aggressiveness predictors.
Helena Espirito-Santo +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Overview of bond mutual funds: A systematic and bibliometric review
Cogent Business & Management, 2021 The focus of this review is to exhibit a thorough analysis of prominent aspects in bond funds literature and their conceptual developments employing the trending bibliometric analysis.
Lithin B M +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Higher Education—Educating for Higher Order Skills
Creative Education, 2013 Preparing college students for a knowledge-based economy is a challenge that requires curriculum design that puts more emphasis on learning skills than on content to be taught. Cognitive skills should be practiced in a context of some content, but the choice of content, the choice of the learning environment, and the choice of the assessment procedures
openaire +2 more sources
Higher Education Exchange: 2009 [PDF]
, 2009 This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share ...
Dana Walker +7 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Higher Education Exchange: 2007 [PDF]
, 2007 This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share ...
Barbar Nesin +8 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source