Results 111 to 120 of about 1,589,637 (346)

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

open access: yesAdvanced Science, EarlyView.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu   +11 more
wiley   +1 more source

Excellence in Professional Disciplines and Their Importance in Social and Educational Entrepreneurship

open access: yesEducation Sciences
Knowledge of the potentialities and strengths of individuals is a premise of numerous studies today, even more so when we are in a historical moment characterized by dizzying changes that demand innovation and creativity from society to adapt to such ...
Alberto Rocha   +3 more
doaj   +1 more source

Physical Informal Learning Environment on Campus Ground: A Review [PDF]

open access: yes, 2017
Past few decades, there has been a raft amplifying interest in higher education institutions, nationally and internationally, in the creation of new types of learning environment supporting learner-centered or constructivist pedagogy. This paper reviews
Aziz, Nor Fadzila   +2 more
core  

'Worldly' pedagogy: a way of conceptualizing teaching towards global citizenship [PDF]

open access: yes, 2012
In this paper, we discuss the characteristics of a form of pedagogy capable of addressing difference across nations and cultures in ways that do not inflate difference.
Cousin, G., Fanghanel, Joelle
core   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

La vie pédagogique des facultés et écoles toulousaines (1808-1968)

open access: yesLes Cahiers de Framespa, 2018
Based on the example of higher education in Toulouse and a comparative approach to teaching practices, this paper focuses on educational developments that took place between 1808 and 1968.
Caroline Barrera
doaj   +1 more source

Engaging the 'Xbox generation of learners' in Higher Education [PDF]

open access: yes, 2007
The research project identifies examples of technology used to empower learning of Secondary school pupils that could be used to inform students’ engagement in learning with technology in the Higher Education sector.
Ahmed, Jebar, Sheard, Mary
core  

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

open access: yesAdvanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen   +10 more
wiley   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

Feminist Collaboration in the Art Academy [PDF]

open access: yes, 1996
Women\u27s activity in the visual arts both in and outside of the art institutions of Europe and the United States reveals a history of collaboration in artistic production and political activism This paper analyzes the effects of feminist collaboration ...
Bickley-Green, Cynthia, Wolcott, Anne G.
core   +1 more source

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