Results 101 to 110 of about 449,112 (270)

Circadian rhythmicity and human health

Biomedical Journal
Our modern lifestyle involves irregular eating habits and extended periods spent indoors under artificial lighting. This lifestyle contrasts with the body's circadian rhythms and likely contributes to an increase of chronic diseases worldwide.
Jan Martel, David M. Ojcius, John D. Young   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Current Trends in Augmented Reality to Improve Senior High School Students’ Skills in Education 4.0: A Systematic Literature Review

Open Education Studies
Augmented reality (AR) became increasingly popular in education worldwide as a useful tool for improving student engagement, teamwork, and problem-solving abilities to enhance students’ skills in Education 4.0 (E4.0).
Yanti Febri, Lufri Lufri, Ahda Yuni
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Commentary on Articles 2 and 3 of the Washington Treaty

, 2019
Both Articles 2 and 3 of the North Atlantic Treaty present the idea that the North Atlantic alliance is more than a military organization, and one that serves to foster peace and the rule of law.
Kačič, Matjaž
core   +1 more source

Perspectives on Lived Religion and Lived Theology

Approaching Religion
This thematic issue brings together current research focused on lived religion and/or lived theology. Several of the articles have been developed from papers presented at the national Research Conference in Theology and Religion held in Turku/Åbo in May
Martina Björkander, Clementine Nishimwe, Sofia Sjö   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

News articles framing of a sports organization

, 2023
Studiens huvudämne är att undersöka hur stora idrottsevenemang presenteras och diskuteras offentligt i samband med företagens sociala ansvar. Syftet med studien är att ta reda på vilka gestaltningar som främst förekommer i nyhetsartiklarna och i vilket ...
Lundgren, Daniel, Gustavsson, Filip, Scherer, Kenny   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The antecedents of purchase intention of local brands: A systematic literature review

Asian Management and Business Review
This study reviews and summarizes empirical findings on the determinants of local brand purchase intentions over the past five years. It aims to provide a comprehensive understanding of the literature for future researchers by using a systematic ...
Emilia Septiani, Ni Nyoman Kerti Yasa, Ni Wayan Ekawati, I Putu Gde Sukaatmadja   +3 more
doaj   +1 more source