Results 201 to 210 of about 449,112 (270)

Editorial: Research in obesity, type 2 diabetes, and metabolic syndrome: cellular pathways and therapeutic innovations. [PDF]

Front Cell Dev Biol
Choubey M, Barua R, Tirumalasetty MB, Wahiduzzaman M, Mohiuddin MS.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Bibliometric characteristics of articles on key competences indexed in ERIC from 1990 to 2013

This paper analyses the bibliometric characteristics of 616 journal articles on key competences indexed in ERIC in a 23-year-period following documentary analysis.
Buscà Donet, Francesc, Ambròs, Alba, Burset Burillo, Sílvia   +2 more
core  

The Epigenetic Horizon: New Molecular Perspectives. [PDF]

Int J Mol Sci
Miceli M.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Editorial: Biomaterials for dental caries prevention and management. [PDF]

Front Oral Health
Akhter R, Hiraishi N, Sanon K, Yu OY.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Evaluating Large Language Models for Post-Publication Promotion: A Blinded Comparative Study of Social Media Posts in Public Health. [PDF]

J Korean Med Sci
Doskaliuk B, Mukhamediyarov M, Yessirkepov M, Zimba O.   +3 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Commentary: A Bibliometric Review of Capsular Contracture in Breast Implant: Global Trends and Research Hotspots. [PDF]

Plast Surg (Oakv)
Hadzimustafic N, Safran T, Vorstenbosch J.   +2 more
europepmc   +1 more source